PURPOSE To investigate the development of smooth pursuit in infants and to assess the influence of different stimulus characteristics. METHODS A total of 131 eye movement recordings were obtained from 71 infants between 1 and 18 months of age using infrared photo-oculography. Smooth pursuit eye movements (SPEM) were stimulated using targets of different sizes (1.2° and 4.7° of visual angle) a...

PURPOSE To identify and explain the effects of eye and head position on smooth pursuit eye movements in normal humans. METHODS Horizontal and vertical smooth pursuit were measured in different eye-in-orbit positions in normal subjects, using a magnetic search coil technique with sinusoidal and step-ramp stimuli. Pursuit also was tested in different horizontal head-on-trunk positions. RESULT...

Recent neurophysiological experiments in the monkey have demonstrated that the flocculus and the posterior vermis, lobules VIc-VII (oculomotor vermis), are involved in the generation of pursuit eye movements. Whereas the functions of the flocculus in the control of smooth pursuit have been intensively investigated, sufficient data are not available for a profitable discussion of the functions o...

We recorded the activity of fixation neurons in the frontal eye field (FEF) in trained monkeys and analyzed their activity during smooth pursuit eye movements. Fixation neurons were densely located in the area of the FEF in the caudal part of the arcuate gyrus facing the inferior arcuate sulcus where focal electrical stimulation suppressed the generation of saccades and smooth pursuit in bilate...

BACKGROUND Abnormal smooth pursuit eye movements have been found in many schizophrenic patients and in about 40% of their first-degree biological relatives. A velocity discrimination deficit has also been demonstrated in schizophrenic patients. In this study, we address the relation between deficient velocity discrimination and impaired smooth pursuit eye movements, inasmuch as the brain region...