BACKGROUND Social isolation in medical students is a subjective experience that may influence medical career decision making. Rural self-efficacy has been shown to influence rural career intentions following a rural clinical placement, however its impact on social isolation during a rural clinical placement has not been previously modeled. The objective of this study is to explore whether self-...

Survey researchers have long hypothesized that social isolation negatively affects the probability of survey participation and biases survey estimates. Previous research, however, has relied on proxy measures of isolation, such as being a marginalized group member within a population. We re-examine the relationship between social isolation and survey participation using direct measures of socia...

OBJECTIVES Maladaptive schemas are stable cognitive working models of the world, learnt early in life, that interfere with effective functioning and underlie chronic mental illness. A major challenge for cognitive therapy has been how to modify schemas when they are so enduring and stable. We propose that because maladaptive schemas are formed through social experiences (typically abusive or ne...

Background: Existing evidence suggest that those who are socially isolated at risk for taking up or continuing smoking. This study investigated country-based differences in social isolation and smoking status.

Social isolation has dramatic long-term physiological and psychological consequences; however, the mechanisms by which social isolation influences disease outcome are largely unknown. The purpose of the present study was to investigate the effects of social isolation on neuronal damage, neuroinflammation, and functional outcome after focal cerebral ischemia. Male mice were socially isolated (ho...

Psychological factors, including depression and social isolation, are important determinants of cardiovascular health. The current study uses a well-validated mouse model of cardiac arrest/cardiopulmonary resuscitation (CA/CPR) to examine the effect of social environment on several pathophysiological and behavioral responses to cerebral ischemia. Male experimental mice were either housed in pai...