conclusions diclofenac-loaded nanoparticles based on properties of chitosan gelation could delay the release of drugs in the stomach and be further evaluated for the enteric delivery of diclofenac. objectives the aim of this study was to prepare and evaluate diclofenac-loaded chitosan nanoparticles based on the ionotropic gelation method. materials and methods chitosan (cs) nanoparticles contai...

citicoline is a natural substance with neuroprotective and repairing effects. it can also increase the phosphor metabolites in cerebral cortex. regarding the various effects of citicoline on central nervous system, this research aims at studying the effects of citicoline on the thiopental sodium anesthesia. six dogs were anesthetized by intravenous injection of 20 mg ∕ kg of 2.5% thiopental sod...

objective studies on the effect of various antiepileptic drugs on serum lipids show contradictory results. we aimed to find the effect of phenobarbital and sodium valproate monotherapy on serum lipid profile and liver function tests in epileptic children. materials & methods this cohort study was conducted in amirkola children hospital. one hundred and ten children with epilepsy were included i...

a simple and efficient one-pot method for the preparation of aromatic iodides has been developed by sequential diazotization–iodination of aromatic amines employing sodium nitrite and sodium iodide in the presence of acidic ionic liquid n-methyl-2-pyrrolidonum hydrosulfate ([h-nmp]hso4). the diazonium salts that are formed by this ionic liquid are stable at room temperature and react rapidly wi...