نتایج جستجو برای: somatic cell nuclear transfer
تعداد نتایج: 2125338 فیلتر نتایج به سال:
Somatic cell nuclear transfer is used to generate genetic models for research and new, genetically modified livestock varieties. Goat fetal fibroblast cells (gFFCs) are the predominant nuclear donors in Cashmere goat transgenic cloning, but have disadvantages. We evaluated the potential of goat adipose-derived mesenchymal stem cells (gADSCs) and goat skeletal muscle-derived satellite cells (gMD...
objective: nuclear transfer-embryonic stem cells (nt-escs) are genetically identical to the donor’s cells; provide a renewable source of tissue for replacement, and therefore, decrease the risk of immune rejection. trichostatin a (tsa) as a histone deacetylase inhibitor (hdaci) plays an important role in the reorganization of the genome and epigenetic changes. in this study, we examined whether...
Cell differentiation is remarkably stable but can be reversed by somatic cell nuclear transfer, cell fusion, and iPS. Nuclear transfer to amphibian oocytes provides a special opportunity to test transcriptional reprogramming without cell division. We show here that, after nuclear transfer to amphibian oocytes, mitotic chromatin is reprogrammed up to 100 times faster than interphase nuclei. We f...
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