نتایج جستجو برای: somatropin
تعداد نتایج: 1761 فیلتر نتایج به سال:
Objectives. Estimate and compare the proportion of cancer patients with cachexia using different definitions from available clinical data. Methods. Electronic medical records were examined to estimate the proportion of cancer patients with cachexia using 4 definitions: (1) ICD-9 diagnostic code of 799.4 (cachexia), (2) ICD-9 diagnosis of cachexia, anorexia, abnormal weight loss, or feeding diff...
OBJECTIVE To identify clinical predictors associated with catch-up growth in the first year of treatment with somatropin (rhGH) in a group of children born small for gestational age (SGA). SUBJECTS AND METHODS Thirty nine children who have been on rhGH therapy for at least one year (0.33 mg/kg/week) were evaluated. The clinical parameters analyzed were chronological age (CA), bone age (BA), t...
Cost-Minimization of Somatropin for GH Deficiency and Turner Syndrome Treatment from SUS Perspective
BACKGROUND The GH-2000 score has been developed as a powerful and unique technique for the detection of growth hormone misuse by sportsmen and women. The score depends upon the measurement of two growth hormone (GH) sensitive markers, insulin-like growth factor-I (IGF-I) and the amino-terminal pro-peptide of type III collagen (P-III-NP). With the collection and establishment of an increasingly ...
The accurate prediction of protein stability is one of the most challenging goals in protein formulation and delivery. In this study, a gradient RP-HPLC method is described for the separation of human growth hormone (hGH) variants as deamidated and oxidized forms. The methodology employed a polymeric poly (styrene-co-divinylbenzene) column and a 1mL/min flow rate of a linear gradient of 0.1% v/...
The Lawson Wilkins Pediatric Endocrinology Society Drug and Therapeutics Committee guidelines for the use of growth hormone were first published in 1983, near the end of the era of human pituitary-derived growth hormone (GH), and again in 1995, a decade after the introduction of recombinant human (rh)GH. The LawsonWilkins Pediatric Endocrine Society also endorsed an international consensus docu...
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