purpose: to evaluate the effectiveness of pars plana vitrectomy and posterior hyaloid stripping in decreasing macular thickness and improving vision in diabetic macular edema.          methods: this prospective interventional case series includes 30 eyes of 25 diabetic patients with diabetic macular edema with macular thickness exceeding 170 microns and thickened posterior hyaloid. bcva and mac...

BACKGROUND Opium is one of the most common substances used worldwide with variable epidemiologic features in different regions. This study was performed in southern Iran, to find the epidemiology of opium use and its association with different factors and diseases. METHODS This cross-sectional study was performed on baseline data extracted from Pars Cohort Study performed in Valashahr, a rura...

Peroxynitrite, a cytotoxic oxidant formed from nitric oxide (NO) and superoxide, induces DNA strand breakage, which activates the nuclear enzyme poly(ADPribose) synthase (PARS; EC 2.4.2.30). The cellular function of PARS was determined in fibroblast lines from PARS knockout animals (PARS2/2) and corresponding wild-type animals (PARS1/1), with the aid of the lipophilic PARS inhibitor 5-iodo-6-am...

OBJECTIVE To determine the most effective and biodegradable dispersant of spilled oil in water surrounding two Persian Gulf provinces. METHODS This study compared the effects of three dispersants, Pars 1, Pars 2, and Gamlen OD4000 on removal of oil in two Persian Gulf provinces' water. Overall, 16 stations were selected. Using the Well method, the growth rate of isolated bacteria and fungi wa...

1Department of Spinal Surgery, Pars Advanced and Minimally Invasive Manners Research Center (PAMIM), Pars Hospital, Tehran, Iran 2Adventist Hinsdale Hospital,120 N Oak St, Hinsdale, IL 60521, USA *Corresponding author Abolfazl Rahimizadeh, MD Department of Spinal Surgery Pars Advanced and Minimally Invasive Manners Research Center (PAMIM) Pars Hospital, Tehran, Iran Tel. + 98 912 322 61 49 E-ma...

The cellular origins of corticotropin and melanotropin were studied by observing the response of the rat hypophysis to adrenalectomy and cortisol administration when stained immunochemically with peroxidase-labeled antibody following application of antiserums to P1-24-corticotropin, pp17-39-corticotropin, human p-melanotropin, and a-melanotropin. The presence of corticotropin in the pars interm...

Proteinase-activated receptors (PARs) belong to a family of G protein-coupled receptors, thus mediating the cellular effects of proteinases. In the vascular system, thrombin and other proteinases in the coagulation-fibrinolysis system are considered to be the physiologically relevant agonists, whereas PARs are among the most important mechanisms mediating the interaction between the coagulation...

BACKGROUND Paternal age related schizophrenia (PARS) has been proposed as a subgroup of schizophrenia with distinct etiology, pathophysiology and symptoms. This study uses a k-means clustering analysis approach to generate hypotheses about differences between PARS and other cases of schizophrenia. METHODS We studied PARS (operationally defined as not having any family history of schizophrenia...