Primary sarcomas of the kidney are exceptional. Among renal sarcomas, leiomyosarcoma is the most common histologic subtype amounting to 50-60% of all cases. The tumor usually arises from either the renal capsule or smooth muscle tissue in the renal pelvic wall. In this paper, we report a patient with leiomyosarcoma of the kidney presented with non-specific abdominal pain and a palpable mass....

dear editor:   we thank dr asadi amoli for her interest in our article. 1 dr asadi amoli pointed out that specific and sensitive rhabdomyosarcoma (rms) markers should be investigated in our case. 2 we agree with dr asadi amoli ’s opinion and are sorry that the results of pathology examination and myogenin (myf-4) staining studied in a local hospital were not provided in our case report.   an ex...

over the past few decades, actin’s presence in the nucleus has been demonstrated. actin is a key protein necessary for different nuclear processes. although actin is well known for its functional role in dynamic behavior of the cytoskeleton, emerging studies are now highlighting new roles for actin. at the present time there is no doubt about the presence of actin in the nucleus. a number of st...

Actin network architecture and dynamics play a central role in cell contractility tissue morphogenesis. Pulsed contractions driven by RhoA represent generic mode of actomyosin contractility, but the mechanisms underlying (1) how their specific emerges, (2) this supports contractile function network, remain unclear. Here, we combine quantitative microscopy, single-molecule imaging, numerical sim...

The actin cytoskeleton executes a broad range of essential functions within a living cell. The dynamic nature of the actin polymer is modulated to facilitate specific cellular processes at discrete locations by actin-binding proteins (ABPs), including the formins and tropomyosins (Tms). Formins nucleate actin polymers, while Tms are conserved dimeric proteins that form polymers along the length...

primary sarcomas of the kidney are exceptional. among renal sarcomas, leiomyosarcoma is the most common histologic subtype amounting to 50-60% of all cases. the tumor usually arises from either the renal capsule or smooth muscle tissue in the renal pelvic wall. in this paper, we report a patient with leiomyosarcoma of the kidney presented with non-specific abdominal pain and a palpable mass. hi...