Two XRF specimen preparation methods were investigated for quantifying gallium in plutonium metal. Gallium in plutonium was chosen here as an example for demonstrating the efficacy of wavelength dispersive XRF for quantifying radioactive materials. The steps necessary to handle such materials safely will also be discussed. Quantification of plutonium samples by a wellestablished aqueous specime...

Accurate full-length genomic sequences are important for viral phylogenetic studies. We developed a targeted high-throughput whole genome sequencing (HT-WGS) method for influenza A viruses, which utilized an enzymatic cleavage-based approach, the Nextera XT DNA library preparation kit, for library preparation. The entire library preparation workflow was adapted for the Sentosa SX101, a liquid h...

Electron crystallography studies the structure of two-dimensional crystals of membrane proteins or other crystalline arrays. This method has been used to determine the atomic structures of six membrane proteins and tubulin, as well as several other structures at a slightly lower resolution, where secondary structure motifs could be identified. To preserve the high-resolution structure of 2D cry...

Transmission electron microscopy (TEM) is a widely used tool for analysis of very large scale integrated (VLSI) semiconductor devices. As a special TEM-feature, off-axis electron holography obtains information about the electrical characteristics of a specimen, which are connected to the dopant concentration in the bulk material. Compared with conventional TEM, application of electron holograph...