BACKGROUND Comparison of air versus saline for loss of resistance technique (LORT) in combined spinal epidural labor analgesia (CSE) has not been evaluated, and neither has the relation between CSE characteristics (the presence/absence of initial spontaneous clear fluid return or upon aspiration) and spinal/epidural analgesia outcomes. The authors hypothesized that there is no difference in the...

Suppression of spinal responses to noxious stimulation has been detected using spinal fMRI during placebo analgesia, which is therefore increasingly considered a phenomenon caused by descending inhibition of spinal activity. However, spinal fMRI is technically challenging and prone to false-positive results. Here we recorded laser-evoked potentials (LEPs) during placebo analgesia in humans. LEP...

The addition of opioids to local anesthetics improves the analgesic potency of spinal analgesia. The purpose of this study was to evaluate the efficacy and safety of intrathecal fentanyl 15 microg when added to lidocaine 80 mg in patients undergoing Cesarean section under spinal anesthesia. Forty healthy parturients scheduled for elective Cesarean section using 80 mg of 5% lidocaine were random...

BACKGROUND AND AIMS Regional analgesia is commonly used for the relief of labour pain, Prolongation of analgesia can be achieved by adjuvant medications. The aim of this randomised controlled trial was to evaluate the efficacy of intrathecal levobupivacaine with dexamethasone for labour analgesia. METHODS A total of 80 females were included in this study, all were primigravidas undergoing vag...

Background: To study the efficacy of spinal analgesia with low concentration bupivacaine for anorectal surgery as compared to low dose bupivacaine epidural analgesia. Methods: This randomized control study was conducted on 60 adult patients undergoing elective anorectal surgery. The patients were randomly allocated into one of three groups of 20 patient’s each. The two treatment arms received s...

background: spinal analgesia is one of the effective and rapid methods for labor. it is not commonly used because of short duration of analgesia and motor block, which limits mother's force in labor progression. we attempted to prolong duration and quality of analgesia by adding epinephrine. methods: in this quasi-experimental study 90 pregnant women gravid ii and iii who referred to motazedi a...

Purpose: In this study we sought to determine if and when a difference exists with regards to differential sensory blockade between spinal and epidural anaesthesia using lidocaine. Methods : Ten healthy volunteers were randomly assigned to receive both spinal and epidural anaesthesia. Nonepinephrine containing solutions of lidocaine, 100 mg lidocaine 5% with 7.5% dextrose (spinal) and 600 mg li...

conclusions the addition of 50 mg of magnesium sulfate to a bupivacaine–fentanyl solution for intrathecal anesthesia improved the efficacy and duration of the analgesia without any significant side effects. the addition of 150 µg of neostigmine increased the incidence of hypotension, bradycardia, and nausea and vomiting. moreover, neostigmine failed to prolong analgesia duration. results group ...