The small GTPase Ras is critical for regulation of growth and differentiation during development. The mammalian protein RIN1 is a potential Ras effector protein, which can also interact with the Abelson tyrosine kinase. However, its biological function is unknown. We have identified the Drosophila homologue of RIN1, called sprint, for SH2, poly-proline containing Ras interactor. The sprint locu...

Objective: This investigation aimed to compare the effect of neuromuscular, strength and combined training on dynamic balance and sports performance including sprint, agility and power abilities in female basketball players. Method: In this semi-experimental study, 42 female professional basketball players (age 19-25 years) were assigned to three groups (neuromuscular (NM), strength (ST), and ...

Performance in sprint exercise is determined by the ability to accelerate, the magnitude of maximal velocity and the ability to maintain velocity against the onset of fatigue. These factors are strongly influenced by metabolic and anthropometric components. Improved temporal sequencing of muscle activation and/or improved fast twitch fibre recruitment may contribute to superior sprint performan...

To assess the impact of 'top-up' normoxic or hypoxic repeat-sprint training on sea-level repeat-sprint ability, thirty team sport athletes were randomly split into three groups, which were matched in running repeat-sprint ability (RSA), cycling RSA and 20 m shuttle run performance. Two groups then performed 15 maximal cycling repeat-sprint training sessions over 5 weeks, in either normoxia (NOR...

This study investigated the feasibility and reliability of a 12 × 25-m repeated sprint test with sprints starting every 25-s in children aged 6-8 years (36 boys, 41 girls). In all subjects, total sprint time (TST) demonstrated high test-retest reliability (ICC: r = .98; CV: 0.7% (95% CI: 0.6-0.9)). While sprint time varied over the 12 sprints in all subjects (p < .001) with a significant increa...

Research is inconclusive regarding the association between aerobic fitness (objectively measured VO2max) and repeated sprint performance when the sprints are less than 40 meters. Soccer athletes must be able to repeat sprints without significant decreases in speed and strength and conditioning coaches need to better understand if aerobic fitness is related to repeated sprint ability (RSA). Twen...

Objectives: The purpose of this study was to assess the practical use of heavy sled towing and its acute implications on subsequent sprint acceleration performance. Design and Methods: Eight healthy male varsity team sport athletes (age: 21.8 ± 1.8years, height: 185.5 ± 5.0cm, weight: 88.8 ± 15.7kg, 15m sprint time: 2.66 ± 0.13s) performed sprints under three separate weighted sled towing condi...

We examined the effects of sprint training on left ventricular diastolic stiffness during normoxia and after ischemia-reperfusion (I/R). Thirty-seven, male Sprague-Dawley rats, weighing 150-175 g at the initiation of the experiment, were randomly assigned to a sedentary, control group (n = 20) or to a high-intensity, sprint-trained group (n = 17). Animals were trained 5 days/wk on a motor-drive...

Locomotor performance is linked to fitness and health of animals and is expected to be under strong selection. However, interindividual variation in locomotor performance is pronounced in many species. It was our aim to investigate the relative importance of energy metabolism and calcium handling in determining sprint and sustained locomotion in the zebrafish (Danio rerio). Sprint and sustained...

Eight male subjects volunteered to take part in this study. The exercise protocol consisted of ten 6-s maximal sprints with 30 s of recovery between each sprint on a cycle ergometer. Needle biopsy samples were taken from the vastus lateralis muscle before and after the first sprint and 10 s before and immediately after the tenth sprint. The energy required to sustain the high mean power output ...