BACKGROUND The purpose of this study was to investigate the rate of simultaneous second primary tumor (SPT) in patients with oral squamous cell carcinoma. The survival of patients with simultaneous SPT was also compared with patients without. METHODS The presence of SPT was documented along with the patients' demographic data, tumor-related features, and survival status. Kaplan-Meier method w...

BACKGROUND We developed skin prick test (SPT) reagents for common inhalant allergens that reflected the real exposure in Korea. The study aim was to evaluate diagnostic usefulness and allergen potency of our inhalant SPT reagents in comparison with commercial products. METHODS We produced eight common inhalant allergen SPT reagents using total extract (Prolagen): Dermatophagoides farinae, Der...

UNLABELLED Serine palmitoyltransferase (SPT) is a key enzyme in the first step of sphingolipid biosynthesis. Mutations in the SPTLC1 gene that encodes for SPT subunits cause hereditary sensory neuropathy type 1. However, little is understood about how mutant SPT regulates mechanisms of sensory neuron and axonal growth. Using transgenic mice overexpressing the C133W SPT mutant, we found that mut...

CEPIS, Council of European Professional Informatics Societies, is a non-profit organisation seeking to improve and promote high standards among informatics professionals in recognition of the impact that informatics has on employment, business and society. CEPIS unites 36 professional informatics societies over 32 European countries, representing more than 200,000 ICT professionals. UP GRADE is...

Primary hyperoxaluria type 1 (PH 1), an inborn error of glyoxylate metabolism characterized by excessive synthesis of oxalate and glycolate, is caused by a defect in serine:pyruvate/alanine:glyoxylate aminotransferase (SPT/AGT). This enzyme is peroxisomal in human liver. Recently, we cloned SPT/AGT-cDNA from a PH 1 case, and demonstrated a point mutation of T to C in the coding region of the SP...

BACKGROUND Skin prick test (SPT) and fluorescence enzyme immunoassay (FEIA) are widely used for the diagnosis of Immunoglobulin-E (IgE)-mediated allergic disease. Basophil activation test (BAT) could obviate disadvantages of SPT and FEIA. However, it is not known whether BAT gives similar results as SPT or FEIA for aeroallergens. OBJECTIVES In this study, we compared the results of SPT, BAT a...

The standard penetration test (SPT) has been widely used because of its usability, economy, and many correlations with soil properties among other factors. In SPT, hammer energy is an important factor to evaluate and calibrate N values. To measure hammer energy, an instrumented SPT rod was developed considering that stress waves transferring on rods during SPT driving are the same as stress wav...

BACKGROUND An enhancement in recall of simple instructions is found when actions are performed in comparison to when they are verbally presented - the subject-performed task (SPT) effect. This enhancement has also been found with older adults. However, the reason why older adults, known to present a deficit in episodic memory, have a better performance for this type of information remains uncle...

Sodium polytungstate (SPT) is currently the material of choice for soil density fractionation (DF). We recently detected high levels of N in several types of commercially available SPT (0.74– 1.4 mg g), raising a concern that undesirable chemical effects on soils may occur during the DF procedure. To address this concern, we conducted two experiments to examine effects of SPT on C and N in the ...

A solid pseudopapillary tumour of the pancreas (SPT) is a rare neoplasm accounting for less than 2% of exocrine pancreatic neoplasms. SPT occurs in adolescent young females and is mostly benign. It is a low-grade malignant tumour that may evolve years before symptoms start and has a favourable prognosis. In this report we present five cases (four females, one male, aged 16, 45, 23, 17 and 55 ye...