Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1) is known to function as a negative feedback regulator of cytokine signaling, but it is unclear whether it is involved in other biological events. Here, we show that SSI-1 participates and plays an important role in the insulin signal transduction pathway. SSI-1-deficient mice showed a significantly low leve...

BACKGROUND Recent studies have shown a lower risk of surgical site infections (SSI) after laparoscopic distal gastrectomy compared to open surgery. This is a phase 2 study aiming to determine the incidence of SSI after laparoscopic distal gastrectomy without using antimicrobial prophylaxis (AMP). METHODS cT1N0 gastric cancers that were subject to laparoscopic distal gastrectomy were enrolled....

Introduction / objectives Surgical-site infections (SSI) account for about 24% of hospital infections. Due to short postoperative staying, SSI diagnosis is eventually made after discharge. SSI rates may be under reported; therefore surveillance after discharge is needed to obtain reliable indices of SSI and to improve quality of care. Aim: To describe the SSI rate assessed after discharge and t...

BACKGROUND Deep and organ/space surgical site infections (D/OS SSI) cause significant morbidity, mortality, and costs. Rates are publicly reported and increasingly used as quality metrics affecting hospital payment. Lack of standardized surveillance methods threaten the accuracy of reported data and decrease confidence in comparisons based upon these data. METHODS We analyzed data from nation...

The impact of curricular reform efforts that are incorporated into the Statewide Systemic Initiatives (SSIs) program were examined at the item level using data from the 1990, 1992, and 1996 NAEP state administrations. The item-level data from the State NAEP for grade 8 from 1990, 1992, and 1996 and for grade 4 from 1992, and 1996 were examined applying methodology developed for the study of dif...

The performance of recently introduced Surgical Stress Index (SSI), based on heart rate and photoplethysmography, was estimated during sevoflurane-fentanyl and isoflurane-fentanyl anesthesia during surgical procedures. Forty ASA I-III patients were enrolled. Anesthesia was induced with fentanyl 2 mug kg(-1) and thiopentone 3-5 mg kg(-1). Tracheal intubation was performed 5 minutes after fentany...

Over three-fourths of the working-age population in the United States is insured for Disability Insurance (DI); this group is protected against a total loss of earned income typically associated with severe disability. However, little is known about the role the Supplemental Security Income (SSI) program plays in protecting against the financial consequences of severe disability for this popula...

BACKGROUND Control of surgical site infections (SSI) is imperative for the safety of our patients. As orthopedic surgeons we strive to have the lowest infection rate possible for all our surgical procedures. this study evaluates the effects of a simple outpatient peri-operative patient cleaning protocol (The Steiros Algorithm(®) Outpatient Surgery Protocol) on SSI rates. METHODS We retrospect...

INTRODUCTION The Erection Hardness Score (EHS), recently validated, was developed in 1998 as a simple (one-item) method to quantify erection outcome data. Although it is intuitive that erection hardness and successful sexual intercourse (SSI) are related, the link has not been directly established. OBJECTIVE To evaluate the relationship between erection hardness (assessed by EHS) and SSI, est...

Surgical site infection (SSI) has not been extensively studied in musculoskeletal tumors (MST) owing to the rarity of the disease. We analyzed incidence and risk factors of SSI in MST. SSI incidence was evaluated in consecutive 457 MST cases (benign, 310 cases and malignant, 147 cases) treated at our institution. A detailed analysis of the clinical background of the patients, pre- and postopera...