Abstract Background The overall objective was to prepare a highly accurate nanocarrier system of mesalamine for the treatment ulcerative colitis with increased therapeutic efficacy and targeting. In formulation systems, optimization is critical process understanding nanoformulation variables quality aspects. goal present work determine effect independent variables, i.e., concentrations chitosan...

The computerization of method development and validation are useful in analysis of pharmaceuticals in pharmaceutical industry. In this article a simple and rapid high performance liquid chromatographic method has been developed for the determination of oxcarbazipine in pharmaceutical formulations. Factorial design was applied for optimization of essential factors for robustness study. A linear ...

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Where fuzzy regression can be applied and, in which conditions fuzzy regression method more appropriate tool for the investigations are identified in this paper. The contrast between fuzzy regression and ordinary regression analysis and three approach of fuzzy regression are summarized. In this paper, we estimated the values of the parameters in the factorial experiment in the textile industry ...

Identification of significant process parameters using experiments needs to be carefully formulated as it can be a resource demanding process. Using appropriate statistical techniques such as the Taguchi method of factorial design of experiments, the number of necessary experiments can be reduced and the statistical significance of parameters can be safely identified. In the case of linear fric...

This study suggests two approaches to factorial invariance testing with multilevel data when the groups are at the within level: multilevel factor mixture model for known classes (ML FMM) and multilevel multiple indicators multiple causes model (ML MIMIC). The adequacy of the proposed approaches was investigated using Monte Carlo simulations. Additionally, the performance of different types of ...

Conjoint analysis studies typically utilize orthogonal fractional factorial experimental designs to construct a set of hypothetical stimuli. Occasionally, these designs include environmentally correlated attributes that can lead to stimulus profiles that are not representative of the subject’s environment. To date, no one has proposed a remedy well-grounded in statistical theory. This note pres...