BACKGROUND AND OBJECTIVES We reviewed our case-load of patients with Toxic Epidermal Necrolysis (TEN) and analysed this oncologic disease in order to define the prevalence of this comorbidity and find eventual clinical and prognostic differences, specific of this subgroup of patients. MATERIALS AND METHODS We reviewed charts from January 1995 to December 2005. Only those patients with a TEN d...

Erythema Multiforme (EM) is specific acute hypersensitivity syndrome of multiple etiologies. It has distinct clinical pattern the hallmark of which, is the erythematous rash (so called iris or target lesions). Although a single type of lesion may predominate during a particular attack, the basic lesion of erythema multiforme are macular, urticarial and vesicobullous. The diagnosis of Erythema m...

Background: Immune checkpoints inhibitors (ICIs) are widely used in various therapy of tumors. With the increasing usage them, immune-related adverse events (irAEs) have been known and become common events, especially dermatologic system. However, rare severe cutaneous (irCAEs) still lack enough knowledge. Case presentation: We described a case Steven-Johnson syndrome (SJS) induced by pembroliz...