REPORT OF A CASE SUCCESSFUL PREGNANCY AND DELIVERY FOLLOWING DRUG REACTION STEVENS-JOHNSON SYNDROME

BACKGROUND It was proposed that Stevens-Johnson syndrome and toxic epidermal necrolysis differed from erythema multiforme majus by the pattern and localization of skin lesions. OBJECTIVE To evaluate the validity of this clinical separation. DESIGN Case-control study. SETTINGS Active survey from 1989 to 1995 of 1800 hospital departments in Europe. PATIENTS A total of 552 patients and 172...

AIM Stevens Johnson syndrome and toxic epidermal necrolysis are severe acute mucocutaneous diseases. In this study, we evaluated the clinical aspects of Steven Johnson syndrome, toxic epidermal necrolysis and Stevens-Johnson syndrome/toxic epidermal necrolysis overlap patients who admitted to our clinics in the last five years. MATERIAL AND METHODS Eleven patients diagnosed as Stevens-Johnson...

AIMS To understand the immunopathogenesis of the corneal conjunctivalisation in Stevens-Johnson syndrome. METHODS Conjunctivalised corneas from five patients with Stevens-Johnson syndrome were studied immunohistochemically for several cell surface antigens and two cytokines. Chemical injury specimens were also studied. RESULTS In all cases, immunohistochemistry revealed LFA-1, CD4, CD8, and...

drugs are an important cause of stevens–johnson syndrome(sjs) in about 95% of reports. 100 drugs have been reported as causes of sjs or toxic epidermal necrolysis (ten). there are very few reports of sjs due to use of diclofenac. in this report we present a 65 year old lady who developed sjs after usage of diclofenac suppository.

Non-steroidal anti-inflammatory drugs are commonly prescribed in dental practice after minor oral surgical procedures such as tooth extraction. Diclofenac sodium is one of the non-steroidal antiinflammatory drugs widely used for pain relief in dentistry. Although adverse reactions to these drugs are rare, at times they can cause a life-threatening phenomenon. Stevens-Johnson syndrome is one suc...

OBJECTIVE To assess the type of severe skin reactions caused by valdecoxib treatment. DESIGN Case registry of severe skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis. SETTING All hospitals in Germany that treat patients with severe skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis. PATIENTS Five case notifications of Stevens-Johns...

Stevens-Johnson syndrome has been an acute, usually self-limiting disease of the skin and mucous membranes. This case report has presented an evidence of the development Stevens - Johnson syndrome associated with combination chemotherapy administration of 5FU, gemcitabin and cisplatin in a patient with biliary tract cancer. Our case was a 54-year-old woman patient, a case of biliary tract cance...