this study examines the empirical validity of claims that value stocks (stocks with high ratios of book value to price) have higher average returns than growth stocks (stocks with low book-to-market ratios). the analyses are performed using data pertaining to 70 firms for the period 1381-1389 and used the panel data methodology. this paper contains significant and consistent results. the result...

A lentivirus-based packaging system was designed to reduce the chance of recombination between helper and gene transfer vector sequences by using the constitutive transport element (CTE) derived from Mason-Pfizer monkey virus for expression of the viral proteins and the Rev-Rev response element (RRE) combination for expression of the gene transfer vector. Using this approach, we evaluated a ser...

Five species members of the Korean Hyrcanus Group: Anopheles pullus, Anopheles sinensis, Anopheles kleini, Anopheles belenrae, and Anopheles lesteri were tested for susceptibility to Brugia malayi. They were allowed to feed artificially on blood containing B. malayi microfilariae and dissected 14 days after feeding. The susceptibility rates were 60%, 65%, 90%, 100% and 100% in An. pullus, An. s...

Recombinant adeno-associated virus (rAAV) vectors have many advantages for gene therapeutic applications compared with other vector systems. Several methods that use plasmids or helper viruses have been reported for the generation of rAAV vectors. Unfortunately, the preparation of large-scale rAAV stocks is labor-intensive. Moreover, the biological titration of rAAV is still difficult, which ma...

This study provides a principal component analysis-fuzzy-support vector regression model for stock price prediction. Stocks with similar historical trends are selected using principal component analysis. Fuzzy information granulation is performed to construct a probability density for stock prices. Support vector regression is implemented to generate a regression function for future price predi...

In portfolio optimization, the inverse covariance matrix prescribes the hedge trades where a portfolio of stocks hedges each one with all the other stocks to minimize portfolio risk. In practice with finite samples, however, multicollinearity makes the hedge trades too unstable to be reliable. By reducing the number of stocks in each hedge trade to curb estimation errors, we motivate a “sparse”...

A method for rapidly producing helper-free murine leukemia virus (MLV) without using packaging cell lines is described. Viruses bearing ecotropic or amphotropic MLV or Rous sarcoma virus envelope glycoprotein and containing various retroviral vector genomes have been prepared with titers 30 to 40-fold higher than those produced by transient transfection of standard packaging cells. This system ...