First identified in 1975, the relationship between migraine and stroke has received considerable attention. Forty years later, solid evidence indicates that those with migraine have a 1.5-fold to 2.5-fold increased risk of stroke. However, the strength of this relationship varies based on the subtypes of migraine (with vs without aura) and stroke (hemorrhagic vs ischemic). While the majority of...

A complex bidirectional relation between migraine, mostly migraine with aura (MA), and ischaemic stroke is known. A cerebral infarction can occur during a MA, and MA is a risk factor for ischaemic stroke, particularly in young women. Conversely, cerebral ischaemia can induce MA. Both ischaemic stroke and MA might be consequences of many underlying vascular disorders. Despite the relation betwee...

Numerous studies have indicated an increased risk for stroke in patients with migraine, especially migraine with aura; however, many studies used self-reported migraine and only a few controlled for familial factors. We aimed to investigate migraine as a risk factor for stroke in a Swedish population-based twin cohort, and whether familial factors contribute to an increased risk. The study popu...

Stroke is one of the main causes of death and disability worldwide, and only in Sweden approximately 25 000 individuals suffer from stroke each year. This thesis focuses on two common conditions; migraine and patent foramen ovale (PFO) and their role in stroke. Migraine is a common primary headache disorder, affecting approximately 11-13 % of the population with a 3:1 female preponderance. One ...

BACKGROUND Migraine is recognised increasingly as a risk factor for ischaemic stroke in women of childbearing age. Migraine with aura poses a higher risk than migraine without aura. OBJECTIVE To investigate further the effect of duration, frequency, recency, and type of migraine on the risk of ischaemic stroke. METHODS Additional analyses of a previously reported multicentre case-control st...

OBJECTIVES To examine the association between migraine and migraine aura status with risk of haemorrhagic stroke. DESIGN Prospective cohort study. SETTING Women's Health Study, United States. PARTICIPANTS 27,860 women aged >or=45 who were free from stroke or other major disease at baseline and had provided information on self reported migraine, aura status, and lipid values. MAIN OUTCOM...

INTRODUCTION Migraine has consistently been associated with increased risk of ischemic stroke, while the evidence for a relation with other types of stroke or coronary outcomes is limited. We examined the association between migraine and stroke and acute coronary syndrome (ACS) subtypes and the influence of potential confounding factors. METHODS All first-time hospital contacts for stroke (n=...

BACKGROUND AND PURPOSE The etiology of headache in stroke is not known, and its relation to migraine and tension-type headache is unclear. The aim of our study was to investigate and classify headache appearing in stroke patients prospectively, using the new headache classification as determined by the Headache Classification Committee of the International Headache Society (1988). METHODS Two...