Hardware implementation of partially-parallel Low-Density Parity-Check (LDPC) decoders using unstructured random matrices is very complex and requires huge hardware resources. To alleviate the complexity and minimize resource requirements, structured LDPC matrices are used. This paper presents a novel technique for constructing a multi-level Hierarchical Quasi-Cyclic (HQC) structured matrix for...

the molecular dynamics (md) simulation method is used to assess structural details for humanprion protein (hereafter prpn) and its asp178 asn mutant (hereafter prpm) which causes fatalfamilial insomnia disease. the results reveal that the flexibility and instability increase in prpmcould be related to specific amino acids exposed to the solvent. solvation free energy of prpm is 20kjmot1nni2 mor...

One of the major problems in computational drug design is incorporation of the intrinsic flexibility of protein binding sites. This is particularly crucial in ligand binding events, when induced fit can lead to protein structure rearrangements. As a consequence of the huge conformational space available to protein structures, receptor flexibility is rarely considered in ligand design procedures...

In this paper, A flexibility-based method for damage identification of cantilever-type structures is proposed. Using the linear relation between flexibility matrix element and structure parameter, the damage equation involving modal parameter and damage coefficient of each structure element is established firstly. Then, using the free vibration response signal of structure and the time-frequenc...

The issues surrounding the use of ambient vibration modes for the location of structural damage via dynamically measured flexibility are examined. Several methods for mass-normalizing the dynamic mode shapes extracted from ambient modal data are implemented and compared. The methods are applied to data from a series of ambient modal tests on an actual highway bridge. The results indicate that t...

The objective of this study was to develop a new optimal parallel algorithm for matrix multiplication which could run on a Fibonacci Hypercube structure. Most of the popular algorithms for parallel matrix multiplication can not run on Fibonacci Hypercube structure, therefore giving a method that can be run on all structures especially Fibonacci Hypercube structure is necessary for parallel matr...

Fibronectin (Fn) is an essential extracellular matrix (ECM) glycoprotein involved in both physiological and pathological processes. The structure-function relationship of Fn has been and is still being studied, as changes in its molecular structure are integral in regulating (or dysregulating) its biological activities via its cell, matrix component, and growth factor binding sites. Fn comprise...

T paper examines how the optimal investment in the capacity of flexible and nonflexible resources is affected by financial leverage and, conversely, how a firm’s resource flexibility affects its optimal capital structure. We consider a two-product firm that invests in the optimal capacity of product-flexible and productdedicated resources in the presence of demand uncertainty. Before investing ...

β-lactamases are bacterial enzymes that confer resistance to β-lactam antibiotics, such as penicillins and cephalosporins. There are four classes of β-lactamase enzymes, each with characteristic sequence and structure properties. Enzymes from class A are the most common and have been well characterized across the family; however, less is known about how physicochemical properties vary across th...