نتایج جستجو برای: subacute toxicity test

تعداد نتایج: 930958  

Journal: :Toxicology and Applied Pharmacology 1969

Journal: :Japanese Journal of Oral Biology 1975

Background: Diazinon (Dzn), an Organophosphorus (OP) pesticide, is extensively used in agriculture. Acetylcholinesterase inhibition is linked to OP toxicity, and there are major mental health concerns associated with the use of pesticides. The objective of this study was to assess the depressive behavior in an animal model following their exposure to Dzn and the effect on the Brain-Derived Neur...

Journal: :Australian veterinary journal 1982
P J Ketterer B J Blaney C J Moore I S McInnes P W Cook

Five cases of aflatoxicosis in pigs in southern Queensland are described. One peracute case where aflatoxin concentrations of up to 5000 micrograms aflatoxin B1/kg were demonstrated in stomach contents was presumed to be caused by consumption of mouldy bread. High levels of toxins were also present in the livers. Two cases of acute toxicity were caused by feeding mouldy peanut screenings contai...

2014
Wiriyaporn Sumsakul Tullayakorn Plengsuriyakarn Wanna Chaijaroenkul Vithoon Viyanant Juntra Karbwang Kesara Na-Bangchang

BACKGROUND Plumbagin is the major active constituent in several plants including Plumbago indica Linn. (root). This compound has been shown to exhibit a wide spectrum of biological and pharmacological activities. The present study aimed to evaluate the in vitro and in vivo antimalarial activity of plumbagin including its acute and subacute toxicity in mice. METHODS In vitro antimalarial activ...

Journal: :Toxicological research 2015
Chung-Tack Han Myoung-Jun Kim Seol-Hee Moon Yu-Rim Jeon Jae-Sik Hwang Chunja Nam Chong-Woo Park Sun-Ho Lee Jae-Bum Na Chan-Sung Park Hee-Won Park Jung-Min Lee Ho-Song Jang Sun-Hee Park Kyoung-Goo Han Young Whan Choi Hye-Yeong Lee Jong-Koo Kang

Lithospermum erythrorhizon has long been used as a traditional oriental medicine. In this study, the acute and 28-day subacute oral dose toxicity studies of hexane extracts of the roots of L. erythrorhizon (LEH) were performed in Sprague-Dawley rats. In the acute toxicity study, LEH was administered once orally to 5 male and 5 female rats at dose levels of 500, 1,000, and 2,000 mg/kg. Mortality...

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