The implantable cardioverter defibrillator (ICD) has had an enormous impact on the treatment of patients with lifethreatening ventricular arrhythmias. It has been shown not only to be effective in reducing mortality in patients who have survived a potentially life-threatening ventricular arrhythmia (1) but also to improve outcomes when used as primary prevention for sudden cardiac death in pati...

We examine dynamic asymmetries in U.S unemployment using nonlinear time series models and Bayesian methods. We nd strong statistical evidence in favor of a two-regime threshold autoregressive model. Empirical results indicate that, once we take into account both parameter and model uncertainty, there are economically interesting asymmetries in the unemployment rate. One nding of particular inte...

The subcutaneous implantable cardioverter-defibrillator (S-ICD) is a novel technology with proven efficacy in sudden cardiac death prevention; however, there is a lack of long-term safety data. We describe the case of a 55-year-old female patient implanted with an S-ICD due to idiopathic ventricular fibrillation, who subsequently presented with inappropriate shocks leading to ventricular fibril...

A 58 year-old male was referred to our institute for recurrent palpitations followed by ICD shocks. The patient had a history of ischemic cardiomyopathy (EF 25%) and had received a dual-chamber ICD two years earlier for primary prevention of sudden cardiac death. The device interrogation showed multiple episodes of tachycardia and anti-tachycardia pacing (ATP), which frequently terminated the t...

Atrioventricular Junction Ablation Transvenous ablation of the atrioventricular (AV) junction was first performed with direct-current shocks in 1981.1 Radiofrequency energy replaced direct-current shocks for AV junction ablation because of improved efficacy and safety.2 Radiofrequency ablation of the AV junction has a success rate .95% and is associated with a low incidence of adverse effects.3...

A key application of long memory time series models concerns innation. Long memory implies that shocks have a long-lasting eeect. It may however be that empirical evidence for long memory is caused by neglecting one or more level shifts. Since such level shifts are not unlikely for innation, where the shifts may be caused by sudden oil price shocks, we examine whether evidence for long memory (...

BACKGROUND AND OBJECTIVES Implantable cardioverter-defibrillators (ICDs) are indicated in patients with Brugada syndrome (BS), early repolarization syndrome (ERS), or idiopathic ventricular fibrillation (IVF) who are at high risk for sudden cardiac death. The optimal ICD programming for reducing inappropriate shocks in these patients remains to be determined. We investigated the difference in t...

Sudden disruptions, or shocks, to food production can adversely impact access to and trade of food commodities. Seafood is the most traded food commodity and is globally important to human nutrition. The seafood production and trade system is exposed to a variety of disruptions including fishery collapses, natural disasters, oil spills, policy changes, and aquaculture disease outbreaks, aquafee...

While economic downturns have adverse effects on young people's life chances, empirical studies examining whether and to what extent human values, social attitudes and well-being indicators respond to sudden economic shocks are scarce. To assess the claim that human values are less affected by economic shocks than social attitudes and well-being, two distinct yet related studies based on the Eu...