Background: Several virulence factors have been described in pathogenesis of Staphylococcus aureus strains. Staphylococcal Enterotoxins(SEs) that is one of the most factors, are belonging to important members of bacterial superantigens. Superantigens are defined by their ability to stimulate cytokine release from both T cells and macrophages. 13 different SEs are known that their function is no...

....................................................................................9 INTRODUCTION: .......................................................................11 RISK FACTORS OF BREAST CANCER ..............................................11 Age ..........................................................................................11 Reproductive factors .............................

Cross-correlation of super-resolution images gathered from point localizations allows for robust quantification of protein co-distributions in chemically fixed cells. Here this is extended to dynamic systems through an analysis that quantifies the steady-state cross-correlation between spectrally distinguishable probes. This methodology is used to quantify the co-distribution of several mobile ...

Western Blot analysis. Protein concentration was measured using BCA kit (Thermo Scientific, Rockford, IL, USA) and protein lysates were separated by SDS-PAGE and then blotted onto Hybond-C extra membranes (GE Healthcare, Buckinghamshire, UK) for Western blot analysis. Antigen-antibody reaction was detected using Super Signal West Pico and Femto chemiluminescent substrate kits according to manuf...

results the mean age of chb patients was 38.5± 11.9 years and 55.9% of them (231 patients) were male. there were 13 cases (3.1%) with hdv infection. there was no association between positive anti-hdv serology and factors such as age, gender, carrier state, liver enzymes, and positive hepatitis b e antigen (hbeag) serology. conclusions although hdv had a low prevalence in our area, it is importa...

The great success of anti-cytotoxic lymphocyte antigen 4 (CTLA4) and anti-programed cell death protein 1 (PD1) in cancer treatment has encouraged more effort in harnessing the immune response through immunomodulatory molecules in various diseases. The immunoglobulin (Ig) super family comprises the majority of immunomodulatory molecules. Discovery of novel Ig super family members has brought nov...

trichomoniasis, the most widespread sexually transmitted disease is caused by trichomonas vaginalis. this parasite is site specific for the genitourinary tract and recruitment of macrophages as well as polymorphonuclear nutrophils (pmn) to the site of infection is the first line of defense as a component of non-specific resistance and immunity. in this study, balb/c mice were infected with 10 i...

The B and T lymphocyte attenuator (BTLA) is an Ig super family member that binds to the herpes virus entry mediator (HVEM), a TNF receptor super family (TNFRSF) member. Engagement of BTLA by HVEM triggers inhibitory signals, although recent evidence indicates that BTLA also may act as an activating ligand for HVEM. In this study, we reveal a novel role for the BTLA-HVEM pathway in promoting the...

Improving labeling probes for state-of-the-art super-resolution microscopy is becoming of major importance. However, there currently a lack tools to quantitatively evaluate probe performance regarding efficiency, precision, and achievable resolution in an unbiased yet modular fashion. Herein, we introduce designer DNA origami structures combined with DNA-PAINT overcome this issue quantification...