There is a need for new materials and architectures for tissue engineering and regenerative medicine. Based upon our recent results developing novel scaffold architecture, we hypothesized that this new architecture would foster vascularization, a particular need for tissue engineering. We report on the potential of superporous hydrogel (SPH) scaffolds for in vivo cellular infiltration and vascu...

While the discovery of highly potent biologics has led to the development of promising therapies for various human diseases, biologics can cause severe toxicity if delivered inappropriately. Thus, great efforts have been made to synthesize polymeric systems for safe and efficient delivery of biologics. However, the application of polymeric delivery systems is often limited by problems such as h...

This work reports the synthesis and use of zeolites based super-porous hydrogel composites (SPHCs) as solid polymer desiccants to capture water vapors from moist air. The SPHCs were composed hydrogels (SPHs) acrylic acid methacrylamide (i.e. P(AA-co-MAM)-SPHs) matrix AQSOA type zeolites, i.e. AQSOA-Z01, AQSOA-Z02 AQSOA-Z05 reinforcing materials. Different structural morphological properties cha...

The objective of the present investigation is to formulate Nizatidine loaded superporous floating hydrogel tablets. In the present study Nizatidine floating tablets were prepared by effervescence method using sodium bicarbonate as a gas generating agent. The tablets were formulated using direct compression technology by employing polymers like chitosan, carbopol 934p and ethyl cellulose. The pr...

Superporous hydrogels (SPHs) swell to a large size in a very short time. In many applications it is preferred to compress SPHs to reduce the overall dimension in the dried state. The effects of compression on the swelling property of SPHs were examined. The swelling property of the compressed SPHs was dependent on the orientation of the SPHs during compression. If SPHs were compressed in an ori...