One-tone rate suppression has been reported several times for auditory nerve fibers of mammalian and non-mammalian vertebrates. Because its properties are very similar to those of two-tone rate suppression, the possibility exists that one-tone rate suppression is the result of an interaction within the inner ear of the suppressing tonal stimulus and some ongoing extraneous acoustic stimulus. Fo...

background: several studies have demonstrated the immunosuppresive effects of mes-enchymal stem cells (mscs) in allogeneic or mitogenic interactions. cell-cell contact inhibition and secretion of suppressive soluble factors have been suggested in this re-gard. objective: to investigate if adipose derived mscs could inhibit jurkat lym-phoblastic leukemia t cell proliferation during coculture. me...

Due to restrictive tolerancing in microfabrication, structural imperfections that reduce performance of fabricated micro devices are typical. In microelectromechanical vibratory gyroscopes, feedback control is a common strategy in attempting to correct the imperfections. However, a purely feedback control can be insufficient for compensation of all the errors, requiring post processing in the f...

The interrelationship between drug-induced changes in heart rate and drug-induced alterations in ventricular automaticity was studied in dogs with intact conduction systems and dogs with surgically-induced complete heart block. The effects of epinephrine (0.5 microgram-kg-1-min-1) and propranolol (1.0 mg-kg-1) on ventricular automaticity were shown to be partially concealed by heart rate change...

Due to a lack of integration between different sensors, false alarms (FA) in the intensive care unit (ICU) are frequent and can lead to reduced standard of care. We present a novel framework for FA reduction using a machine learning approach to combine up to 114 signal quality and physiological features extracted from the electrocardiogram, photoplethysmograph, and optionally the arterial blood...

Burst suppression is a unique electroencephalogram (EEG) pattern commonly seen in cases of severely reduced brain activity such as overdose of general anesthesia. It is important to detect burst suppression reliably during the administration of anesthetic or sedative agents, especially for cerebral-protective treatments in various neurosurgical diseases. This study investigates recurrent plot (...