Genetic aberrations contribute to acute myeloid leukemia (AML). However, half of AML cases do not contain the well-known aberrations detectable mostly by cytogenetic analysis, and these cases are classified as normal karyotype AML. Different outcomes of normal karyotype AML suggest that this subgroup of AML could be genetically heterogeneous. But lack of genetic markers makes it difficult to fu...

Crinum asiaticum L. and latifolium are members of the family Amaryllidaceae. Karyomorphological studies these two species had been performed by using different quantitative qualitative parameters to know karyotype asymmetry, which defines advanced primitive nature species. The study revealed that diploid with 2n=22 chromosomes. based on Total Chromatin Length, Arm Ratio, Gradient Index, Form Pe...

BACKGROUND We previously found that a normal karyotype in a previous miscarriage is a predictor of subsequent miscarriage. However, the prevalence of recurrent miscarriage caused by an abnormal embryonic karyotype has not yet been reported, since embryonic karyotype is not typically analyzed during conventional examinations. METHODS A total of 482 patients who underwent both embryonic karyoty...

background : turner syndrome (ts) is a sporadic disorder caused by the absence of all or some parts one x-chromosome with major developmental consequences such as short stature and ovarian failure etc. the minor manifestations of ts are cubitus valgus, micrognatism, high-arched palate, short and/or webbed neck, hypothyroidism, etc. different karyotype abnormalities may lead to different clinica...

Rheum palmatum, one of the source plants of the traditional Chinese medicine rhubarb, is anendemic and endangered species. To our knowledge, this is the first report on the chromosome number and karyotype of this species. Sectioning combined with micrography was used to analyze the karyotype. The following results were obtained: R. palmatum had a stable chromosome number 2n = 22; the basic numb...

In optimization, one of the main challenges widely used family Quasi-Newton methods is to find an estimate Hessian matrix as close possible real matrix. this paper, we develop a new update formula for starting from Powell-Symetric-Broyden (PSB) and adding pieces information previous steps optimization path. This lead multisecant version PSB, which call generalised PSB (gPSB), but does not exist...

the karyotype of zagros tooth-carp, aphanius vladykovi (coad) has been investigated byexamining metaphase chromosomes spreads obtained from gill epithelial and kidney cells. the diploidchromosome number of this species was 2n=48. the karyotype consisted of 8 submetacentric and 40subtelocentric chromosomes (8sm+40 st). the arm number (nf) was 28. sex chromosomes werecytologically indistinguishab...

Placental mesenchymal dysplasia (PMD) is a rare benign placental abnormality. It is characterized by hydropic degeneration of stem villi, placentomegaly, and increased maternal serum alpha-fetoprotein(AFP). It can be associated with different congenital abnormalities, karyotype abnormalities, and feto-maternal morbidities. It is difficult to differentiate PMDfrom partial mole, complete mole wit...

introduction: most of the hematologic malignancies are heterogenous with regard to morphology, immunophenotype, and genetic rearrangements. multiple recurrent chromosomal aberrations have been identified by conventional cytogenetic analysis, which is now widely recognized as one of the most important diagnostic and prognostic determinants in these patients. patients and methods: bone marrow sam...