We investigate whether maple syrup is a suitable sweetener in the management of type 2 diabetes using the Otsuka Long-Evans Tokushima Fatty (OLETF) rat. The enhancement in plasma glucose (PG) and glucose absorption in the small intestine were lower after the oral administration of maple syrup than after sucrose administration in OLETF rats, and no significant differences were observed in insuli...

BACKGROUND Xylitol, a commonly used sweetener, is effective in preventing dental caries. As it inhibits the growth of pneumococci, we evaluated whether xylitol could be effective in preventing acute otitis media (AOM). DESIGN Altogether, 857 healthy children recruited from day care centers were randomized to one of five treatment groups to receive control syrup (n = 165), xylitol syrup (n = 1...

During our systematic search for natural product-based anti-protein misfolding agents for the putative treatment of Alzheimer’s disease (AD), we investigated maple syrup. Canada is the world’s largest producer of maple syrup, accounting for 80% of global output; 2013 annual production was 46 million litres. Maple syrup is produced by thermal evaporation of the sap from maple (Acer) trees, a pro...

Maple syrup urine disease (MSUD) is an inherited disorder of branched-chain amino acid metabolism presenting with life-threatening cerebral oedema and dysmyelination in affected individuals. Treatment requires life-long dietary restriction and monitoring of branched-chain amino acids to avoid brain injury. Despite careful management, children commonly suffer metabolic decompensation in the cont...

OBJECTIVE The primary objective was to assess the warming sensation caused by IFF Flavour 316282 in a syrup used for short-term treatment by patients suffering from nasal congestion and mild to moderate body pain, headache, fever or sore throat associated with an upper respiratory tract infection. METHODS A single cohort, single treatment arm, open-label study. Subjects received one 30 mL dos...

Sir, We read with great interest the article by Eby [1]. We agree with the author that ionic zinc content of the lozenges may be one of the factors responsible for the beneficial effect in common cold. Some other relevant negative factors include zinc lozenges producing side-effects and compromising the compliance as well as masking, higher than therapeutic dose of zinc being used in some of th...

Results of a collaborative study are reported for the detection of added beet or cane sugar in maple syrup by the site-specific natural isotope fractionation-nuclear magnetic resonance (SNIF-NMR) method. The method is based on the fact that the deuterium content at specific positions of the sugar molecules is different in maple syrup from that in beet or cane sugar. The syrup is diluted with pu...

OBJECTIVE In September 2006, a Panamanian physician reported an unusual number of patients with unexplained acute renal failure frequently accompanied by severe neurological dysfunction. Twelve (57%) of 21 patients had died of the illness. This paper describes the investigation into the cause of the illness and the source of the outbreak. METHODS Case-control and laboratory investigations wer...

date syrup, date concentrate and date liquid sugar are among the products which are produced from low quality dates in date processing plants. the aim of this research was to investigate chemical characteristics and sensory properties of date syrup, date concentrate and date liquid sugar in comparison with sugar (sucrose) solutions and evaluate possible substitution of sucrose with these date b...