T he pump performance of the left ventricle (LV) depends on its ability to cycle between two states: 1) a compliant chamber in diastole that allows the LV to fill from a low left atrial pressure and 2) a stiff chamber in systole that ejects the stroke volume at arterial pressure. The transitions from diastole to systole (contraction) and from systole to diastole (relaxation) are essential for t...

We study the Weyl chamber length compactification both of Hitchin and maximal character varieties determine therein an open set discontinuity for action mapping class group. This result is obtained as a consequence canonical decomposition geodesic current on surface finite type arising from topological along special geodesics. show that each component either associated to measured lamination or...

In mitral incompetence the left ventricle has two exits and it has been suggested that diminished resistance to emptying causes left ventricular systole to be shorter than normal (Brigden and Leatham, 1953). Theoretically the elevation of left ventricular end-diastolic pressure that is found in severe mitral incompetence (Ross et al., 1958; Nixon, 1961a) should result in prolongation of systole...

Left ventricular relaxation is dependent on afterload conditions during systole. An abrupt increase in afterload while the ventricle is actively contracting prolongs the duration of systole. An increase in afterload during ventricular relaxation shortens the duration of systole. Therefore, we hypothesized that the point during systole when an abrupt increase in afterload had no effect on the du...

Previous experiments showed the cases in which end ejection of the ventricle did not always coincide with end systole as identified by the time for Emax corresponding to the maximally contracted pressure-volume relationship line of the ventricle. The purpose of the present study is to obtain a better insight into the ventricular afterloading conditions that enable end ejection to coincide with ...

SKINNER,N. SHELDON, JR., JERE H. MITCHELL, ANDREW G. WALLACE, AND STANLEY J. SARNOFF. Hemodynamic e#kts of altering the timing of atrial systole. Am. J. Physiol. 205(3) : 499-503. I g63.-The use of heart block dog preparations allowed an investigation at constant ventricular rates of the hemodynamic effects which resulted when the timing of atria1 systole was altered relative to ventricular sys...

SKINNER,N. SHELDON, JR., JERE H. MITCHELL, ANDREW G. WALLACE, AND STANLEY J. SARNOFF. Hemodynamic e#kts of altering the timing of atrial systole. Am. J. Physiol. 205(3) : 499-503. I g63.-The use of heart block dog preparations allowed an investigation at constant ventricular rates of the hemodynamic effects which resulted when the timing of atria1 systole was altered relative to ventricular sys...