نتایج جستجو برای: tanshinone iia sodium sulfonate tss

تعداد نتایج: 205156  

2016
Chunming Jiang Wei Zhu Xiang Yan Qiuyuan Shao Biao Xu Miao Zhang Rujun Gong

Acute kidney injury (AKI) remains challenging for clinical practice and poses a risk of developing progressive chronic kidney disease (CKD) with no definitive treatment available yet. Tanshinone IIA, an active ingredient of Chinese herbal Salvia miltiorrhiza, has been widely used in Asia for the remarkable organoprotective activities. Its effect on established AKI, however, remains unknown. In ...

Objective(s): Vascular smooth muscle cells (VSMCs) play a key role in the pathogenesis of diabetic vascular disease. Our current study sought to explore the effects of tanshinone IIA on the proliferation and migration of VSMCs induced by advanced glycation end products (AGEs). Materials and Methods: In this study, we examined the effects of tanshinone IIA by cell proliferation assay and cell mi...

Journal: :American journal of physiology. Heart and circulatory physiology 2009
Jiangqin Liu Jude Morton Margaret Miedzyblocki Tze Fun Lee David L Bigam Tai Fai Fok Chao Chen Shoo K Lee Sandra T Davidge Po-Yin Cheung

In traditional Chinese medicine, tanshinone IIA is a lipid-soluble component of Danshen that has been widely used for various cardiovascular and cerebrovascular disorders, including neonatal asphyxia. Despite promising effects, little is known regarding the hemodynamic effects of tanshinone IIA in newborn subjects. To examine the dose-response effects of sodium tanshinone IIA sulfonate (STS) on...

2013
Ji Hoon Jung Tae-Rin Kwon Soo-Jin Jeong Eun-Ok Kim Eun Jung Sohn Miyong Yun Sung-Hoon Kim

Though tanshinone IIA and cryptotanshinone possess a variety of biological effects such as anti-inflammatory, antioxidative, antimetabolic, and anticancer effects, the precise molecular targets or pathways responsible for anticancer activities of tanshinone IIA and cryptotanshinone in chronic myeloid leukemia (CML) still remain unclear. In the present study, we investigated the effect of tanshi...

2016
Hung-Chen Chen Pei-Yi Chen Ming-Jiuan Wu Mi-Hsueh Tai Jui-Hung Yen

Tanshinone IIA, one of the most pharmacologically bioactive phytochemicals isolated from Salvia miltiorrhiza Bunge, possesses several biological activities such as anti-inflammation, anti-cancer, neuroprotection and hypolipidemic activities. In this study, we aim to investigate the hypocholesterolemic effect of tanshinone IIA in hepatic cells. We demonstrated that tanshinone IIA significantly i...

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