نتایج جستجو برای: tc99m mibi
تعداد نتایج: 1158 فیلتر نتایج به سال:
BACKGROUND AND OBJECTIVE The tracer tachnetium-99m-2-methoxy-isobutyl-isonitrile (Tc99m-sestaMIBI) has recently been shown to concentrate in some neoplastic tissues, including myeloma. We investigated the diagnostic capacity and limits of this procedure in tracing focal myeloma lesions, and compared them with those of conventional radiological procedures (Xr). DESIGN AND METHODS We studied 55...
Objectives: Multidrug resistance (MDR), which may be due to the over expression of P-glycoprotein (Pgp) and/or MRP, is a major problem in neoadjuvant chemotherapy of osteosarcoma. The aim of this study was to investigate the role of Tc-99m MIBI scan for predicting the response to pre-operative chemotherapy. Materials and Methods: Twenty-five patients (12 males and 13 females, aged between 8 and...
(99m)Tc-methoxyisobutyl isonitrile (MIBI) is a suitable transport substrate for the multidrug resistance gene product P-glycoprotein (P-gp) and widely used for tumor imaging. Bromocriptine has been shown to inhibit the ATPase activity and the function of P-gp. We hypothesized that bromocriptine could promote the accumulation of MIBI by inhibiting P-gp activities, a feature that can be taken adv...
The Ni atom in the title complex, (C(24)H(20)P)(2)[Ni(C(9)H(17)NO(2)S(3))(2)], lies on a twofold axis within a square-planar geometry defined by four S atoms derived from two dithio-carbimate dianions, each forming a four-membered chelate ring. A small distortion, described by a deviation of the Ni(II) atom by 0.083 (1) Å from the plane through the four S atoms, and also by the torsion angles a...
Crossed McMurry reactions of bifuran- or bithiophenedicarbaldehydes with bipyrroledicarbaldehydes have been studied for the first time. Only those porphycenic macrocycles derived from homocoupled McMurry products were formed. The results are explained by using both density functional theory and electron propagator computations to model the electron affinity of the dialdehyde starting materials....
Radionuclide Tc99m DTPA (Diethylenetriaminepenta Acetic Acid) renal imaging is being used to assist in the evaluation of overall GFR, the intra-renal transit time, the cortical transit time, response to frusimide injection, diagnosis of ATN and rejection in renal transplant cases. A study was conducted at PINSTECH in order to prepare DTPA kit locally and evaluate the labeling efficiency as well...
CD133 mesenchymal cells were enriched using magnetic microbead anti-CD133 antibody from bone marrow mononuclear cells (BMMNCs). Flow cytometry and immunocytochemistry analysis using specific antibodies revealed that these cells were essentially 89 ± 4% CD133(+) and 8 ± 5% CD34(+). CD133(+)/CD34(+) BMMNCs secrete important bioactive proteins such as cardiotrophin-1, angiogenic and neurogenic fac...
OBJECTIVE The purpose of this study was to clarify the usefulness of 99mTc-sestamibi (MIBI) delayed imaging in the assessment of the severity of myocardial ischemia in patients with coronary artery stenosis. METHODS Forty-three angina pectoris with coronary stenosis of greater than 75% were enrolled in this study. Myocardial perfusion SPECT images were obtained 1 and 6 hours after an intraven...
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