MicroRNAs (miRNAs) are small non-coding RNAs that inhibit gene expression by binding to the 3' untranslated region (3'-UTR) of their target mRNAs. Recent studies show that miR-497 plays an important role in various cancers. Here, we summarize the existing studies of miR-497 as following: (1) miR-497 expression in cancer; (2) regulation mechanisms of miR-497 expression; (3) function of miR-497 i...

Large-scale analysis of the GC-content distribution at the gene level reveals both common features and basic differences in genomes of different groups of species. Sharp changes in GC content are detected at the transcription boundaries for all species analyzed, including human, mouse, rat, chicken, fruit fly, and worm. However, two substantially distinct groups of GC-content profiles can be re...

spatial distribution of thermal regions is dependent on local factors and circulation patterns in long terms. recognition of spatial distribution of temperature in geographical regions could be help on planning and environmental policies. the aim of this paper is recognition and detachment of thermal regions in iran. for this object, maximum daily temperature data have been provided using 620 s...

The multivariate calibration problem deals with inference concerning an unknown value of a covariate vector based on observation response vector. Two distinct scenarios are considered in the problem: controlled where covariates non-stochastic, and random random. Under calibration, interest is computation confidence region for that computing prediction Assuming standard normal linear regression ...