Avtor zagovarja tezo, da je Newtonova vzpostavitev razlikovanja med absolutnim in relativnim gibanjem, tj. zavrnitev opredelitve gibanja v razmerju do zaznavnih stvari, »Sholiji o času, prostoru, mestu gibanju« iz Matematičnih principov filozofije narave veliki meri rezultat njegovega kritičnega obračuna z Descartesovo filozofijo narave. To razvidno primerjave »Sholije«, kateri Descartes sicer ...

cleotide (Greider and Blackburn, 1985). Two essential components for telomerase enzymatic To better understand the requirements for telo-merase-mediated telomere addition in vivo, we devel-activity have been defined in a variety of organisms: a protein catalytic subunit with similarity to reverse tran-oped an assay in S. cerevisiae that creates a chromosome end immediately adjacent to a short t...

Telomeres in ageing and cancer Capping of chromosome ends is essential for the stability of linear chromosomes. It requires a minimum length of telomeric DNA, which can be synthesized and elongated by the enzyme telomerase. In addition, functional telomeres depend on the coordinated expression of a group of proteins that bind to telomeric DNA. These proteins are known as components of the shelt...

the specialized structures at chromosome ends, consist of long stretches of protein-bound TTAGGG repeats [1]. In certain cell types, such as germ cells and stem cell populations, the length of telomeric DNA is maintained by the enzyme telo-merase. Most somatic cells, however, lack sufficient telomerase; consequently, telomeric DNA shortens progressively with each cell division. Upon reaching a ...