uclear imaging of the heart is fast emerging as a valuable and widely used non-invasive procedure, that reveals vital information about cardiac structure, physiology, perfusion and metabolism. Commonly perfonned nuclear imaging techniques in cardiology are radionuclide ventriculography (RNV) done by labelling autologous red blood cells with Technetium-99m (Tc-. 99m) and myocardial perfusion ima...

The role of the inert (lone) pair of electrons in thallium(I) salts is studied by comparison of the compounds [Tl@18-crown-6]+ X- (X = TlI4, ClO4) and [K@18-crown-6]+ ClO4-. In contrast to common introductory chemistry textbook opinions, the paradigm that s-p hybridization is a prerequisite for an inert electron pair to become stereochemically active in compounds of the heavier main group eleme...

OBJECTIVES We sought to assess the comparative diagnostic accuracy of adenosine versus exercise in conjunction with thallium-201 scintigraphy for the detection and localization of coronary artery disease in patients with left bundle branch block on the rest electrocardiogram (ECG). BACKGROUND Patients with left bundle branch block on the rest ECG frequently have artifactual reversible septal ...

For crystalline compounds containing Tl, Bi, P, and S, greatly improved chemical shift resolution was observed in 31P magic angle spinning spectra obtained at 21 T relative to spectra obtained at 9.4 T. In Hz units, the spectral linewidths were not strongly dependent on the applied field, which may be a result of a significant contribution to the linewidths from transverse relaxation. Compariso...

The synthesis and cation-binding properties of a series of Calixarene derivatives possessing alkyl chain groups, ester groups and crown ether rings have been investigated. The syntheses of Calix[4]arene crown ethers and Calix[6]arene derivatives possessing alkyl chain, ester group and crown ether ring have been described. In order to evaluate their monovalent cation binding abilities, solvent e...

The kinetics of thallium exchange in cultured rat myocardial cells were studied and compared to those of potassium in the same tissue. Studies were carried out using low concentrations (10 nM to 5 microM) of thallium-204, approximating those likely to be encountered during clinical myocardial scintigraphy. Both thallium uptake and release could be described by a single exponential with a half-t...

Tris(2-pyridonyl)methanes may be synthesized via the reactions of the respective 2-pyridone with CHX3 (X = Cl, Br) and K2CO3 in the presence of [Bu(n)4N]Br, followed by acid-catalyzed isomerization with camphorsulfonic acid. These compounds provide access to a new class of alkyl ligands that feature oxygen donors and are capable of forming metallacarbatranes and a monovalent thallium alkyl comp...

One can mention the importance of the other 13 group elements (triel elements), aluminium, gallium, indium and thallium. For example, aluminium is the second-most used metal after steel, largely because it is so versatile while nearly all gallium is used today in electronics. Numerous advantageous properties of triel elements are a consequence of the acidity of their compounds – the triel centr...

The initial myocardial uptake of thallium-201 depends on myocardial blood flow distribution. The phenomenon of delayed thallium redistribution after transiently or chronically altered myocardial perfusion has been described. The net myocardial accumulation of thallium-201 after injection depends upon the net balance between continuing myocardial extraction from low levels of recirculating thall...