Visual and auditory information is encoded by sensory neurons that tonically release neurotransmitter at high rates. The synaptic ribbon is an essential organelle in nerve terminals of these neurons. Its precise function is unknown, but if the ribbon could be visualized in a living terminal, both its own dynamics and its relation to calcium and vesicle dynamics could be studied. We designed a s...

The ribbon complex of retinal photoreceptor synapses represents a specialization of the cytomatrix at the active zone (CAZ) present at conventional synapses. In mice deficient for the CAZ protein Bassoon, ribbons are not anchored to the presynaptic membrane but float freely in the cytoplasm. Exploiting this phenotype, we dissected the molecular structure of the photoreceptor ribbon complex. Ide...

In sensory hair cells of auditory and vestibular organs, the ribbon synapse is required for the precise encoding of a wide range of complex stimuli. Hair cells have a unique presynaptic structure, the synaptic ribbon, which organizes both synaptic vesicles and calcium channels at the active zone. Previous work has shown that hair-cell ribbon size is correlated with differences in postsynaptic a...

Photoreceptor ribbon synapses are continuously active synapses with large active zones that contain synaptic ribbons. Synaptic ribbons are anchored to the active zones and are associated with large numbers of synaptic vesicles. The base of the ribbon that is located close to L-type voltage-gated Ca(2+) channels is a hotspot of exocytosis. The continuous exocytosis at the ribbon synapse needs to...

A statistical study of the chromospheric ribbon evolution in H[Formula: see text] two-ribbon flares was performed. The data set consists of 50 confined (62%) and eruptive (38%) flares that occurred from June 2000 to June 2015. The flares were selected homogeneously over the H[Formula: see text] and Geostationary Operational Environmental Satellite (GOES) classes, with an emphasis on including p...

In [LLT] Lascoux, Leclerc and Thibon introduced symmetric functions Gλ which are spin and weight generating functions for ribbon tableaux. This article is aimed at studying these functions in analogy with Schur functions. In particular we will describe: • a Pieri and dual-Pieri formula for ribbon functions, • a ribbon Murnagham-Nakayama formula, • ribbon Cauchy and dual Cauchy identities, • and...

During the research in grand port area of Antalya (coordinates: 36. 829022N; 30. 603739 E), it was observed that a very rare fish belonging to Trachipteridae family stranded Mediterranean Sea. The length fish, which weighs 400 g (TW = 400g), has been measured as 85cm (TL 85cm). without anal fin dorsal with red colour and soft rays, extending from caudal region. In examination made; understood t...

In this paper we consider minors of ribbon graphs (or, equivalently, cellularly embedded graphs). The theory of minors of ribbon graphs differs from that of graphs in that contracting loops is necessary and doing this can create additional vertices and components. Thus the ribbon graph minor relation is incompatible with the graph minor relation. We discuss excluded minor characterisations of m...

Rods are capable of greater slow release than cones contributing to overall slower release kinetics. Slow release in rods involves Ca(2+)-induced Ca(2+) release (CICR). By impairing release from ribbons, we found that unlike cones where release occurs entirely at ribbon-style active zones, slow release from rods occurs mostly at ectopic, non-ribbon sites. To investigate the role of CICR in ribb...