preparation and characterization of thermoresponsive in-situ forming poloxamer hydrogel for controlled release of nile red-loaded solid lipid nanoparticles. nanoparticles (nps) are cleared rapidly from systemic circulation and do not provide sustained action in most cases. to solve this problem, this investigation introduces an erodible in-situ forming gel system as potential vehicles for prolo...

Thermoresponsive immunonephelometry was achieved with biotinylated poly(acrylate) and thermoresponsive gold nanocomposites composed of 13-nm gold nanoparticles and thermoresponsive polymers containing triethylenetetramine and biotin groups. The avidin-biotin interaction was used to model an immunoreaction in order to demonstrate thermoresponsive immunonephelometry. In the absence of avidin, pos...

Magnetic nanoparticles functionalized with thermoresponsive polymers become photoresponsive when attached to plasmonic nanoparticles to form heterodimers. Under solar illumination, the plasmonic particles absorb sunlight and induce localized heating, causing collapse of the thermoresponsive polymer chain and clustering of the dimers that facilitate magnetic separation.

Liquid desiccant air conditioning (LDAC) is an emerging technology able to maintain optimal growing conditions in self-sustained greenhouses powered by solar energy. However, the regeneration of liquid (LD) a bottleneck LDAC. This study investigates six desalination technologies – membrane distillation (MD), reverse osmosis (RO), nanofiltration (NF), forward (FO), thermoresponsive (TR) solution...

Hydrogels are polymer networks swollen in water that characterized by soft mechanics and high permeability. This makes them good candidates for separation membrane technologies. The diffusion is controlled the mesh size of network, this can be made tunable through introduction thermoresponsive polymers. However, still a developing field. To contribute to development, dual dynamic network formed...

Stem cell culture is typically based on batch-type culture, which is laborious and expensive. Here, we propose a continuous harvest method for stem cells cultured on thermoresponsive nanobrush surfaces. In this method, stem cells are partially detached from the nanobrush surface by reducing the temperature of the culture medium below the critical solution temperature needed for thermoresponse. ...

Many bioactive compounds, pharmaceutical proteins, and therapeutic cells are used in medical treatments. Methods for the effective purification of such compounds that retain their activities are greatly needed. This review article describes various types of materials based on thermoresponsive polymers for bioanalysis and bioseparations, e.g., thermoresponsive chromatography and thermally modula...

The shell cross-linked (SCL) thermoresponsive hybrid poly(N-isopropylacrylamide-co-aminoethyl methacrylate)b-polymethyl methacrylate (P(NIPAAm-co-AMA)-bPMMA) micelle consisting of a cross-linked thermoresponsive hybrid shell and a hydrophobic core domain was fabricated via a two-step process: micellisation of P(NIPAAm-co-AMA)-b-PMMA in aqueous solution followed by cross-linking of the hydrophil...

The aim of this study was the formulation and examination of a novel thermoresponsive and bioadhesive, in situ gelling drug delivery system, which can be used in the treatment of oesophageal pain and inflammation. A bioadhesive cellulose derivative (Metolose) 60SH) was used as a thermoresponsive material, because Metolose has thermal gelation properties at certain temperature. The thermal gelat...

We report a novel approach for patterning thermoresponsive hydrogels based on N,N-diethylacrylamide (DEAAm) and bifunctional Jeffamine ED-600 by dip-pen nanolithography (DPN). The direct writing of micron-sized thermoresponsive polymer spots was achieved with efficient control over feature size. A Jeffamine-based ink prepared through the combination of organic polymers, such as DEAAm, in an ino...