1-(8-Hydroxy quinolin-2yl-methyl) thiourea ligand (HTF) was synthesized from 8-hydroxyquinoline and thiourea with formaldehyde by condensation method in N,N-dimethyl foramide medium. The metal complexes Zn(II), Cu(II), Ni(II) and Co(II) were prepared using the 1-(8-hydroxy quinolin-2yl-methyl) thiourea as ligand. The ligand and its metal complexes were characterized by elemental analysis, FT-IR...

A series of thiourea and isothiouronium salt derivatives of the aglycone of teicoplanin was prepared by reaction of the terminal amino group with isothiocyanates, followed by S-alkylation of the thiourea compounds. Unexpectedly, the two classes of derivatives show a similar in vitro antibacterial activity against Gram-positive bacteria. Thiourea compounds, due to the lack of a positively charge...

A variety of organocatalysts were screened for the catalysis of the naphthoquinone monoketal Diels-Alder reaction. In this study we found that Schreiner's thiourea catalyst 10 and Jacobson's thiourea catalyst 12 facilitate the cycloaddition of the sterically hindered naphthoquinone monoketal dienophile 3 with diene 4. The use of thiourea catalysis allowed for the first time the highly selective...

However, the conventional gold recovery process is cyanidation, due to the recent environmental laws; researchers are looking for alternative methods for the recovery of gold. Furthermore, the copper anode slime is one of the most important secondary sources of gold (about 1200 ppm). So, the main objective of the current work is gold separation from copper anode slime as a rich secondary source...

A series of 1-acyl-3-(2'-aminophenyl) thiourea derivatives were designed and synthesized. The structures of all the newly synthesized compounds were identified by IR, elemental analysis, ¹H-NMR and ¹³C-NMR. Their anti-intestinal nematode activities against Nippostrongylus brazilliensis were evaluated in rats by an oral route. Among these compounds, at concentrations of 10 mg/kg of rat, compound...

A series of novel thiourea based receptors (1-12) with different signaling units and spacers have been synthesized for the detection of cyanide ion. Among these receptors, 4,4'-bis-[3-(4-cyanophenyl)thiourea]diphenyl sulfide 6 and 4,4'-bis-[3-(3-cyanophenyl)thiourea]diphenyl sulfide 9 exhibited selective detection of cyanide by the naked-eye as well as by UV-Vis spectroscopy. Furthermore, the c...

Thiourea derivatives display a broad spectrum of applications in chemistry, various industries, medicines and various other fields. Recently, different thiourea derivatives have been synthesized and explored for their anti-microbial properties. In this study, four carbonyl thiourea derivatives were synthesized and characterized, and then further tested for their anti-amoebic properties on two p...

X-Ray diffraction studies reveal that the tunnel inclusion compound formed between 1-tert-butyl-4-iodobenzene and thiourea has an incommensurate relationship between the periodicities of the host and guest substructures along the tunnel axis, representing the first reported case of an incommensurate thiourea inclusion compound.

A bioassay of 1-phenyl-2-thiourea for possible carcinogenicity was conducted using Fischer 344 rats and B6C3F1 mice. 1-Phenyl-2-thiourea was administered in the feed, at either of two concentrations, to groups of 50 male and 50 female animals of each species. The high and low concentrations of 1-phenyl-2-thiourea utilized in the chronic bioassay were, respectively, 120 and 60 ppm for rats and 3...

Thiourea’s reaction with hydrogen peroxide in solution under bleaching conditions at three different pH values has been investigated using 13C NMR spectroscopy. Since this reaction is fast and exothermic, it is essential that short total acquisition times be used to accumulate sufficient data to detect different species formed during the reaction. As the abundance of I3C in the reactants in the...