نتایج جستجو برای: thrombophilic phenomena
تعداد نتایج: 120329 فیلتر نتایج به سال:
Inherited thrombophilia is thought to increase the risk of pregnancy related venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE). Pregnancy is a hypercoagulable state due to the increased concentration of coagulation factors, decreased natural anticoagulants and fibrinolytic activity1. The pregnant woman is therefore at increased risk for VTE and this ...
We read the article by Ozturk et al. [1], in which they reported the frequency of some thrombophilic mutations in eastern Turkey. The authors have defined single nucleotide gene variations of factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase (MTHFR) C677T as thrombophilic mutations. However, as current scientific data do not support an increased risk of thrombosis in...
OBJECTIVE To investigate the impact of inherited thrombophilic factors on the gestational outcome of unselected pregnant women. METHOD A total of 392 women with spontaneous pregnancy were investigated for Factor V Leiden, prothrombin G20210A, and MTHFR C677T mutations. Adverse pregnancy outcomes were recorded. RESULTS Thrombophilic genotypes were significantly higher in women with placental...
Antiphospholipid syndrome (APS) is a thrombophilic condition leading to multiple complications. Primary APS rarely causes primary adrenal insufficiency, but it can be life-threatening. In the present report, patient presents with symptoms and signs of insufficiency subsequent hormone level tests radiological findings led diagnosis insufficiency.
The etiology and pathophysiology of cerebral sinus venous thrombosis (CSVT) in the paediatric population is still poorly understood, and the role of thrombophilic risk factors remains to be elucidated. In our multi-center case-controlled study we studied 46 patients with CSVT diagnosed from April 1996 to December 2003, consecutively referred for thrombophilia work-up. The results of thrombophil...
Migraine is a widespread disorder that affects about 18% of the people, in 2/3 of cases women (1). The concept that migraine could be related to some vascular diseases, such as myocardial infarction or a stroke, have grown over the years, mainly in migraine with aura (2–6). In the last decades, several studies have been carried out to understand if and what the linkage could be. Among these stu...
Thrombophilia is defined as a condition predisposing to the development of venous thromboembolism (VTE) on the basis of a hypercoagulable state. Over the past decades, great advances in the pathogenesis of VTE have been made and nowadays it is well established that a thrombophilic state may be associated with acquired and/or inherited factors. The rare loss-of-function mutations of the genes en...
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