Thymoma is a term that should be restricted to neoplasms of thymic epithelial cells, irrespective of the presence or the number of lymphocytes. The usual location of thymoma is the antrosuperior mediastinum; however, this tumor can also occur in other mediastinal compartments, in the neck, within the thyroid gland, in the pericardial cavity, the pulmonary hilum, within the lung parenchyma, o...

[1] Bertolaccini L, Viti A, Cavallo A, Terzi A. Correlation sometimes implies causation: possible roles of correlation analysis between 18-fluorine-fluorodeoxyglucose positron emission tomography/computed tomography and thymic epithelial neoplasms. Eur J Cardiothorac Surg 2013;44:187–8. [2] Fukumoto K, Taniguchi T, Ishikawa Y, Kawaguchi K, Fukui T, Kato K et al. The utility of [F]-fluorodeoxygl...

thymoma is a term that should be restricted to neoplasms of thymic epithelial cells, irrespective of the presence or the number of lymphocytes. the usual location of thymoma is the antrosuperior mediastinum; however, this tumor can also occur in other mediastinal compartments, in the neck, within the thyroid gland, in the pericardial cavity, the pulmonary hilum, within the lung parenchyma, or t...

The diagnosis of thymic epithelial neoplasm has been a topic of controversy for many years. Reasons for this include the lack of predictive value associated with the morphology of these tumours and the multiplicity of classification schemes and terminologies proposed over the years. Recently, a new classification schema was introduced by the World Health Organization (WHO) in an attempt to stan...

The diagnosis of thymic epithelial neoplasm has been a topic of controversy for many years. Reasons for this include the lack of predictive value associated with the morphology of these tumours and the multiplicity of classification schemes and terminologies proposed over the years. Recently, a new classification schema was introduced by the World Health Organization (WHO) in an attempt to stan...

PAX8 is a paired-box gene important in embryogenesis of the thyroid, Müllerian, and renal/upper urinary tracts, and expression of PAX8 has been previously described in carcinomas from each of these sites. However, a large study including a wide variety of epithelial neoplasms from multiple organ sites other than the thyroid, kidney, or Müllerian system has not been performed. The goal of this s...

Immature T cell neoplasms in three young Holstein cattle with neoplastic involvement of the thymus are described. Case 1, with a precursor T lymphoblastic leukemia (calf form of leukosis), was an 86-day-old female calf. The leukemia was characterized by replacement of the bone marrow and spleen by leukemia cells, but preservation of epithelial frameworks throughout the thymus. The other two neo...