Background: Titanium (Ti) implants are commonly coated with hydroxyapatite (HA). However, HA has some disadvantages such as brittleness, low tensile strength and fracture toughness. It is desirable to combine the excellent mechanical properties of ZrO2 and the chemical inertness of Al2O3 with respect to the purpose of this project which was coating Ti implants with HA-ZrO2-Al2O3 to modify the s...

Titanium alloys are known to nucleate an apatite layer when in contact with simulated body fluid. This improves the bioactivity of titanium implants and accelerates osseointegration. Promoting the formation of hydroxyapatite on biocompatible metals is, therefore, a very important topic of biomaterials research. In this paper, the formation of hydroxyapatite (HA) on the near-beta Ti-13Nb-13Zr al...

In recent years, research on titanium and its alloys had increased significantly for hard tissue replacement and dental applications due to their excellent mechanical properties such as high strength to weight ratio, low density and biocompatibility. However, there are some surface originated problems associated with titanium (Ti): poor implant fixation, lack of osseoconductivity, wear and corr...

Ti-based bulk metallic glasses are of great interest in biomedical applications due to their high corrosion resistance, excellent mechanical properties and good biocompatibility. This article reviews recent progress in the development of Ti-based metallic glasses for the application as biomaterials. Ti-based (Ti­Zr­Cu­Pd, Ti­Zr­Cu­Pd­Sn, and Ti­Zr­Cu­Pd­Nb) bulk metallic glasses without toxic a...

Functionally graded metal-ceramic composite was fabricated by pressure-less sintering. The pure metallic component (Ti) and the pure ceramic component (HA) were located at the ends of a cylindrical specimen. Titanium and-Hydroxyapatite were utilized as a metallic and ceramic layer. The target sample thickness was 6 mm with radius cylindrical 20 mm. The sample was made from the cylindrical type ...

This paper described the development of chitosan composites containing precipitated hydroxyapatite particles for potential applications in orthopaedic surgery or waste water treatment. The synthetic process and morphology of hydroxyapatite were reported. The effects of hydroxyapatite content on the microstructure and mechanical properties of composites were investigated. It was found that the Y...

The study monitored in vitro early response of connective tissue cells and immunocompetent cells to enosseal implant materials coated by different blood components (serum, activated plasma, and plasma/platelets) to evaluate human osteoblast proliferation and synthetic activity and inflammatory response presented as a cytokine profile of peripheral blood mononuclear cells (PBMCs) under condition...

Titanium is widely used as material for permanent implants in orthopedic and dental applications. It is well known that Ti shows a mechanically stable interface towards bone (osseointegration). The good biological properties are due to the beneficial properties of the native oxide (TiO2) that forms on Ti when exposed to oxygen. The native titanium oxide on Ti is usually amorphous and very thin,...