Tilmicosin (TLM) is an important antibiotic in veterinary medicine with low bioavailability and safety. This study aimed to formulate and evaluate physicochemical properties, storage stability after lyophilization, and antibacterial activity of three TLM-loaded lipid nanoparticles (TLM-LNPs) including solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), and lipid-core nanocap...

The increasing interest in metamaterials with negative refractive index has been prompted by a variety of promising optical and microwave applications. Often, the resulting electromagnetic problems to be solve are not analytically derivable; therefore, numerical modeling must be employed and the Transmission Line Modeling (TLM) method constitutes a possible choice. After having greatly simplifi...

BACKGROUND The impact of transoral endoscopic CO(2) laser microsurgery (TLM) for the treatment of Tis, T1, and T2 glottic cancer on local disease control, survival, and laryngeal preservation was investigated. METHODS From October 1999 to February 2008, 48 patients with a previously untreated early laryngeal malignant tumor who had been treated with TLM were enrolled in this study. Overall su...

The current development towards multiple processor cores in personal computers is making distribution and parallelization of simulation software increasingly important. The possible speedups from parallelism are however often limited with the current centralized solver algorithms, which are commonly used in today’s simulation environments. An alternative method investigated in this work utilize...

Dual scattering channel (DSC) schemes naturally extend the transmission line matrix (TLM) numerical method beyond the lines set up by P.B. Johns and coworkers. Conceptually, DSC schemes retain from TLM the typical formal splitting of the computed fields into incident and reflected components, interchanged and scattered between adjacent cells, without yet a need for transmission lines. They gene...

in this paper two nodes to model isotropic and anisotropic media in transmission line matrix method (tlm) are presented. by using these two nodes, the permeability and permittivity of an anisotropic media can be modeled simultaneously. another application of these nodes is in modeling media with permittivity and permeability less than one. in the conventional 2 dimensional tlm, the stubs repres...

The procedure for analysis of electromagnetic field in a cylindrical metallic cavity, based on reflection and transmission characteristic, is presented in the paper. An analysis of procedure efficiency to resonant modes identification is conducted numerically and experimentally verified. As a numerical tool, TLM time-domain method, enhanced with the compact wire model to account for the presenc...

Dual scattering channel schemes extend the transmission line matrix numerical method (Johns’ TLM algorithm) in two directions. For one point, transmission line links are replaced by abstract scattering channels in terms of paired distributions (characteristic impedances are thus neither needed, nor in general defined, e.g.). In the second place, non-trivial cell interface scattering is admitted...

This paper considers the application of numerical techniques to modelling large 3D Extremely Low Frequency (ELF) electromagnetic problems in the time and frequency domains. The environment model consists of three material layers: air, sea and seabed. To represent a coastal region, the sea region is shallow with a variable depth and includes a sloping seabed. The electromagnetic source is a harm...