The International Society for Peritoneal Dialysis recommends the regular application of topical antibiotic-containing preparations in addition to a routine exit site care to reduce the risk of exit site infection (ESI). Among these prophylactic antimicrobial preparations, topical gentamicin is one of the widely used and effective antibiotics for prevention of ESI and peritonitis in peritoneal d...

Clindamycin is a macrolide antibiotic that has been used orally and topically in the treatment of acne vulgaris. Unfortunately, oral administration is associated with pseudomembranous colitis in up to 10% of patients; consequently, it is no longer a generally accepted form of acne therapy. Topical application is an effective, safer alternative. Topical formulations may be extemporaneously prepa...

BACKGROUND Earwax is a common problem in both primary and secondary care. There is uncertainty as to the most effective topical treatment. AIM To assess the evidence concerning the efficacy of topical preparations used for treating earwax. DESIGN OF STUDY Systematic review and meta-analysis. METHOD Searching for randomised controlled trials (RCTs) of relevant studies. Classification of pr...

Alcoholic preparations of Arnica montana are widely used for the topical treatment of various inflammatory diseases. Sesquiterpene lactones (SLs) are mainly responsible for their anti-inflammatory activity. Here we have studied the penetration kinetics of Arnica tinctures prepared from dried Arnica flowers originating from different chemotypes as well as of their respective dominating SLs, hele...

Topical preparations are dosage forms applied to the skin for local therapy. These topical contain several types of bases that used drug formulations. This review aimed determine type base is effective and widely in basil leaf function as antioxidants, antibacterial agents, wound healing. The research method comparative, namely, reviewing articles on formulations products with various concentra...

Antioxidants for facial skin care would be better formulated in a topical form because the active substances will interact longer with skin. Indonesia is known its wealth of natural ingredients that are useful as antioxidants. Research related to has been widely carried out and good content The antioxidant herbal plants secondary metabolites, namely flavonoids, alkaloids, phenolic compounds, ca...

reasonable adult dose and, for this child, 1 mg kg. There are no available data concerning the likely absorption of corticosteroid from a topical preparation such as Eumovate in a child of this age; however, it would be a coincidence if this event were not involved in the development of GPP in this case. While unlikely to be a common occurrence in everyday clinical practice it does appear that ...

To assess the safety of topical agents in the middle ear, animal studies were reviewed. Compared with aminoglycoside-containing preparations, which caused significant loss of hair cells in the basal turn of the cochlea, ofloxacin caused no loss of hair cells, even at concentrations higher than used clinically. Moreover auditory brainstem testing revealed no change in auditory thresholds in the ...

Topical antibacterial agents occupy an important niche of antimicrobial therapy for both inpatients and outpatients. These agents, including antiseptic and antibiotic preparations, are used for prophylaxis and treatment of infection. Prophylactic uses include application for traumatic and surgical wounds, burns, intravascular catheters, and eradication of S. aureus nasal carriage. Topical antib...