ABSTACT Total colonic aganglionosis being an unusual form of Hirschsprung’s disease is described in two children. Both the patients were male, one 8-year old and the other 12-year old. They presented with features of sub acute intestinal obstruction preceded by a past history of chronic constipation since birth and operative intervention for similar complaints few years back. A high index of su...

INTRODUCTION Neonatal intestinal perforation usually occurs at distal small bowel secondary to distal bowel obstruction. The aim of this report is to describe an unusual case of total colonic aganglionosis with an initial presentation of proximal jejunal perforation. PRESENTATION OF CASE A male newborn presented with jejunal perforation on the fifth day of life and was treated by laparoscopic...

In 1886, Harald Hirschsprung first described two cases of infantile constipation with colonic dilation, but he did not suggest any etiology or therapeutic option. Over the past 30 years, many studies have revealed the clinical presentation, radiological and histological diagnoses, surgical procedures, epidemiology, and associated genetics related to colonic dilation. Hirschsprung’s disease (HD)...

BACKGROUND Constipation is one of the most common gastrointestinal disorders particularly in industrialized countries. Incidence of constipation varies from 3.4 % to 27.2% in different societies. Increase in urban population, industrialization of communities, changes in behavioral and nutritional habits and inactivity have increased the number of patients suffering from constipation. OBJECTIV...