Modeccin was extracted from the root of Adenia digitata and purified by gel filtration on Sephadex G-100, ion exchange chromatography on DEAE-cellulose, and affinity chromatography on a column containing immobilized, neuraminidase-treated fetuin. The toxin was eluted from the affinity column with lactose. Polyacrylamide gel electrophoresis of affinity-purified modeccin in the presence of sodium...

Nasal decontamination may be indicated when the anterior nasal passages are contaminated with highly radioactive material or radioactive material with either irritating or toxic properties. Nasal irrigation (wash, rinse, douche, lavage) is an established technique used for other conditions and can be applied in these cases. This paper discusses the rationale and use of nasal irrigation and how ...

1. A toxic constituent is present in the fresh pancreas of dogs before trypsinogen can have been activated. 2. The toxic fraction is present in the beta-nucleoprotein, and therefore is thermostable. 3. It is gradually destroyed by autolysis but can be obtained in concentrated form from a gland which has autolyzed 24 hours. 4. The toxic material is probably protein in nature. 5. Intravenous or i...

A previously described porous organic polymer (NU-POP-1) was evaluated against four representative chemical threats: ammonia, cyanogen chloride, sulfur dioxide, and octane. Ammonia, cyanogen chloride, and sulfur dioxide are examples of toxic industrial chemicals (TICs) spanning the range from highly basic to strong-acid forming substances, while octane is used to assess physical adsorption capa...