The assessment of behavioral changes produced by prenatal or early postnatal exposure to potentially noxious agents requires both the designing of ad hoc tests and the adaptation of tests for adult animals to the characteristics of successive developmental stages. The experience in designing tests is still more limited than in the adaptation of tests, but several tests have already proven their...

Findings to be Addressed by Peer Reviewers The statutory mandate for external scientific peer review (Health and Safety Code Section 57004) states that the reviewer's responsibility is to determine whether the scientific portion of the proposed rule is based upon sound scientific knowledge, methods, and practices. State Water Resources Control Board (State Water Board) staff requests that you m...

BACKGROUND International rules must be followed for testing biosecurity in dental materials. A new brand of restorative material appeared in the market and regulations indicated that it should be tested for toxicity. OBJECTIVES The aim of this study was to determine the 90-day sub chronic toxicity of one triethylene glycol dimethacrylate containing composite (MEDENTAL Light-Cure Composite™) o...

background: faba bean toxicity (favism) is a common condition observed in our region.   objective : to develop a short and simple technique involving the use of riboflavin-deficient rats to test in vivo faba bean toxicity.   methods/results: sprague dawley rats were maintained on a riboflavin-deficient diet and their vitamin b 2 status was monitored by the assay of erythrocyte glutathione reduc...

The clinician may often be uncertain about the presence of digoxin toxicity. This uncertainty is particularly important when the clinician must make initial therapeutic decisions about continuing or discontinuing digoxin. We describe a method that helps to clarify the role of the serum digoxin test in decreasing the uncertainty surrounding the diagnosis and treatment of toxicity. The relation b...