s: 2008 KM Sutherland, PC Edwards, LS Van Winkle. Mechanisms of Pulmonary Tolerance in Female Mice to the Cytotoxicant Naphthalene FASEB J. 22: 918.4 2008 LS Van Winkle and JR Harkema. Oxidant Air Pollution and Childhood Asthma. The Toxicologist Vol 102, S-1, p117 A568. 2008 M.V. Fanucchi, B.M. Kumfer, E.D. Wallis, I.M. Kennedy.Acute Airway Epithelial Injury from Three Different Carbon Particle...

So-called ‘Saharanpur encephalitis,’ with high case fatality, used to occur annually, post-monsoon, in Western districts of Uttar Pradesh (UP). Over 2 decades, Indian Council of Medical Research (ICMR) and National Centre for Disease Control (NCDC) staff failed to diagnose it. A team of volunteer investigators (T Jacob John, virologist; VM Vashishtha, pediatrician; NC Nayak, pathologist; Amod K...

Use of the Internet in developing countries is now growing faster. Internet has created a new conduit not only for communication but also in the access, sharing and exchange of information among scientists. The Internet is now viewed as the world's biggest library where retrieval of scientific literature and other information resources are possible within seconds. Large volumes of toxicological...

One of the many roles of a toxicologist is to determine if an observed adverse event (AE) is related to a previously unrecognized function of a given gene/protein. Towards that end, he or she will search a variety of public and propriety databases for information linking that protein to the observed AE. However, these databases tend to present all available information about a protein, which ca...

Brain tissue may be a valuable specimen in interpretation of postmortem toxicology. The protected and isolated position of the brain eliminates or at least attenuates many of the interpretive challenges with postmortem blood specimens. This study presents data for 30 drug and drug metabolites in cases submitted to the Sedgwick County Regional Forensic Science Center for autopsy examination from...

The principles and procedures employed in a modern forensic toxicology lab are detailed in this review. Aspects of Behavioral and Postmortem toxicology, including certification of analysts and accreditation of labs, chain of custody requirements, typical testing services provided, rationale for specimen selection, and principles of quality assurance are discussed. Interpretation of toxicology r...

In forensic toxicology the main relevant scope of toxicologist is to answer these following questions: which kind of drug is involved? Is the analytical result related to death? Which is the supposed lethal dose? Despite the technological improvement in laboratory medicine, the main questions are apparently unresolved, because the availability of new laboratory instrumentation has sometimes inc...