نتایج جستجو برای: tpoab
تعداد نتایج: 213 فیلتر نتایج به سال:
Objective: To examine the prevalence of thyroid disease and dysfunction including thyroid autoimmunity in Norway. Materials and methods: All inhabitants 20 years and older (94 009) in Nord-Trùndelag were invited to participate in a health survey with a questionnaire and blood samples. Results: The prevalence of former diagnosed hyperthyroidism was 2.5% in females and 0.6% in males, hypothyroidi...
Autoimmune thyroid diseases (AITD) are common, affecting 2-5% of the general population. Individuals with positive thyroid peroxidase antibodies (TPOAbs) have an increased risk of autoimmune hypothyroidism (Hashimoto's thyroiditis), as well as autoimmune hyperthyroidism (Graves' disease). As the possible causative genes of TPOAbs and AITD remain largely unknown, we performed GWAS meta-analyses ...
Introduction and Aim: Thyroid peroxidase (TPO) is a thyroid-specific antigen, the presence of TPO antibodies known to be associated with developing hypothyroidism. In this study we aimed investigate genotypes prevalent for SNP rs2071400 gene its association development autoimmune thyroid disease. Materials Methods: This involved 43 patients hypothyroidism 44 healthy controls. Genotyping (C/T) w...
BACKGROUND Perfluoroalkyl acids (PFASs) are suspected thyroid toxicants, but results from epidemiological studies are inconsistent. OBJECTIVES We examined associations between serum PFASs and thyroid hormones (THs) in a representative, cross-sectional sample of U.S. adults. We hypothesized that people with high thyroid peroxidase antibodies and low iodine would be more susceptible to PFAS-ind...
Introduction: Postpartum thyroiditis (PPT) is an autoimmune disease associated with the presence of thyroid autoantibodies (TAAb) and changes in the morphological characteristics of the thyroid gland. Aim: To investigate the clinical importance of certain immunological and ultrasound thyroid characteristics for the diagnosis of postpartum thyroiditis. Patients and methods: 33 women with PPT and...
BACKGROUND No nationwide epidemiological study evaluating the prevalence of subclinical and overt forms of hypothyroidism and hyperthyroidism has yet been conducted in Korea. This study aimed to evaluate the reference range of serum thyroid stimulating hormone (TSH) and the national prevalence of thyroid dysfunctions in Korea. METHODS Nation-wide cross-sectional data were analyzed from a repr...
PURPOSE The association between autoimmune thyroid diseases (AITDs) and vitamin D deficiency is controversial. We aimed to evaluate the relationship between serum 25-hydroxy-vitamin D3 [25(OH)D3] and anti-thyroid antibody levels. MATERIALS AND METHODS 25(OH)D3, anti-thyroid antibodies, and thyroid function measured in 304 patients who visited the endocrinology clinic were analyzed. The patien...
Objectives. Studies have suggested a correlation between untreated celiac disease and risk for other autoimmune diseases. We investigated the prevalence of thyroid autoimmunity in 12-year-old children (i) with symptomatic celiac disease diagnosed and treated with a gluten-free diet, (ii) with screening-detected untreated celiac disease, and (iii) without celiac disease. Methods. Blood samples f...
Most of the studies have shown a higher risk for subclinical and clinical hypothyroidism, antithyroid autoantibodies [overall antithyroid peroxidase antibodies (TPOAb)], and in general, thyroid autoimmunity, overall in the female gender in patients with sarcoidosis (S). A significantly higher prevalence of clinical hypothyroidism and Graves' disease was also described in female S patients with ...
مقدمه: با توجه به شیوع بیشتر بیماریهای اتوایمیون تیروئید در مناطق با ید کافی و شناخته شدن ایران به عنوان کشور عاری از کمبود ید، در این مطالعه وضعیت اتوآنتیبادیهای تیروپراکسیداز (TPOAb) و آنتیتیروگلوبولین (TgAb) در زنان سالم و مبتلا به هیپوتیروئیدی، هیپرتیروئیدی و گواتر ساده بررسی شده است. مواد و روشها: 1019 زن 20 تا 50 ساله در چهار گروه سالم (130=N) و بیماران با هیپوتیروئیدی (379= N) هیپرت...
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