Eight commonly used spices Syzygium aromaticum, Cinnamonum zeylanicum, Zingiber officinale, Murraya koenigii, Piper nigrum, Trachyspermum ammi, Allium sativum and Allium cepa were tested for in vitro antifungal activity on Aspergillus niger, a causative agent of different destructive disease. Out of eight plant materials used, five showed significant antifungal activity against the test pathoge...

In this study aqueous extract of seeds and leaves of Trachyspermum ammi were evaluated for their ability to detoxify aflatoxin B1 and B2 (AFB1; 100 μg L(-1) and AFB2; 50 μg L(-1)) by in vitro and in vivo assays. Results indicated that T. ammi seeds extract was found to be significant (P < 0.05) in degrading AFB1 and AFB2 i.e., 92.8 and 91.9% respectively. However, T. ammi leaves extract proved ...

Back ground: Ayurvedic medicines play an important role in gastro intestinal problems due to safety and efficacy in it. Hence churna meant for digestive property has been formulated by standard procedures and evaluated by physical and analytical methods. Method: The formulation consists of fine powder (sieve 60 size) of dried rhizomes of Zingiber officinale, fruits of Foeniculum vulgarae, barks...

Individuals with lymphatic filariasis (LF) shows elevated levels of pro-inflammatory cytokines, altered expressions of inflammatory genes and are prone to secondary bacterial infection. Also markers of liver dysfunction were reported to be high with increased filarial infection. Acetaminophen (Paracetamol), an anti-pyretic drug was prescribed to LF individuals along with Diethylcarbamazine and ...

Oxidation of biomolecules such as carbohydrates, proteins, lipids, and nucleic acids results in generation of free radicals in an organism which is the major cause of onset of various degenerative diseases. Antioxidants scavenge these free radicals, thereby protecting the cell from damage. The present study was designed to examine the free radical scavenging potential and oxidative DNA damage p...

Mohammad M. Zarshenas1,2, Mahmoodreza Moein3,4*, Soliman Mohammadi Samani5, Peyman Petramfar6 1Department of Traditional Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran 2Essence of Parsiyan Wisdom Institute, Traditional Medicine and Medicinal Plant Incubator, Shiraz University of Medical Sciences, Shiraz, Iran 3Medicinal Plants Processing Research Centre, Shira...

BACKGROUND To screen methanolic extracts of 26 commonly used Indian spices against nine species of uropathogenic bacteria (Enterococcus faecalis, Staphylococcus aureus, Acinetobacter baumannii, Citrobacter freundii, Enterobacter aerogenes, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa), isolated from clinical samples of a tertiary care hospital for antib...