We examine the relationships of three variables (projected area, migration speed, and traction force) at various type I collagen surface densities in a population of fibroblasts. We observe that cell area is initially an increasing function of ligand density, but that above a certain transition level, increases in surface collagen cause cell area to decline. The threshold collagen density that ...

This article presents a multiscale study on adhesive interactions between graphene and its substrates. First, van der Waals (vdW) interactions between graphene and a SiO2 substrate are studied by fi rst-principle density functional theory (DFT) calculations with dispersion corrections. It is found that the interaction strength is strongly infl uenced by changes of the SiO2 surface structures du...

in the present paper, an analysis was carried out to investigate effects of radiation on a free convection flow bounded by a vertical surface embedded in a porous medium with constant suction velocity. it was under the influence of uniform magnetic field in the presence of a homogenous chemical reaction and viscous dissipation with constant heat and mass flux. the non-dimensional governing equa...

The mechanical wiring between cells and their surroundings is fundamental to the regulation of complex biological processes during tissue development, repair or pathology. Traction force microscopy (TFM) enables determination of the actuating forces. Despite progress, important limitations with intrusion effects in low resolution 2D pillar-based methods or disruptive intermediate steps of cell ...

We postulate that an equivalent continuum structure (ECS) of a single-walled carbon nanotube (SWCNT) is a hollow cylinder with mean radius and length equal to that of the SWCNT, and find the thickness of the ECS so that its mechanical response in free vibrations is the same as that of the SWCNT. That is, for mechanical deformations, the ECS is energetically equivalent to the SWCNT. We use MM3 p...

Focal contacts act as mechanosensors allowing cells to respond to their biomechanical environment. Force transmission through newly formed contact sites is a highly dynamic process requiring a stable link between the intracellular cytoskeleton and the extracellular environment. To simultaneously investigate cellular traction forces in several individual maturing adhesion sites within the same c...

Peridynamics (PD) is a reformulation of the classical continuum mechanics. Its core consists in that weighted integral relative displacement over spatial domain used instead derivative governing equations deformation. Based on an improved technique exerting traction boundary surface, peridynamic motion equation has been proposed within framework peridynamic(PD) theory. It more natural and easie...

free surface modeling plays an important role in some ocean structures design, especially in oscillating water column (owc) devices. boundary element method (bem) is a suitable method for free surface modeling due to its simplicity, quick solving, and low data storage requirement. in this paper, bem was used for free surface modeling in owc chamber and out of it. linear kinematic and dynamic bo...

Cell migration is a key contributor to wound repair. This study presents findings indicating that the liquid crystal based cell traction force transducer (LCTFT) system can be used in conjunction with a bespoke cell traction force mapping (CTFM) software to monitor cell/surface traction forces from quiescent state in real time. In this study, time-lapse photo microscopy allowed cell induced def...

This study was undertaken to compare the myoelectric activity of the upper trapezius muscle before, during, and after intermittent, supine cervical traction. Twelve people with diagnosed disease or injury of the cervical spine served as subjects. Electromyographic recordings were taken from the upper trapezius muscle with bipolar surface electrodes. The subjects were treated with 20 minutes of ...