Oxygen therapy, a lifeline for many critically ill patients, can be delivered in nonintubated patients via several devices. unlike patients with chronic hypoxemia, the long-term comfort and cosmetics of the patient are not a concern of intensivists; instead, the goal is to ensure adequate oxygen delivery to prevent hypoxemia. although hypoxemia is often corrected with oxygen therapy, care shoul...

H YPOXEMIA that may reasonably be defined by an arterial hemoglobin oxygen saturation of less than 90% occurs in 5–10% of patients during one-lung ventilation (OLV). The physiopathology of hypoxemia is complex, and the management of intraoperative hypoxemia during OLV remains a challenge for anesthesiologists. In life-threatening hypoxemia, correct oxygenation should be restored rapidly. This m...

The near-IR cytochrome c oxidase (CCO) signal has potential as a clinical marker of changes in mitochondrial oxygen utilization. We examine the CCO signal response to reduced oxygen delivery in the healthy human brain. We induced a reduction in arterial oxygen saturation from baseline levels to 80% in eight healthy adult humans, while minimizing changes in end tidal carbon dioxide tension. We m...

BACKGROUND Life-threatening acute lung injury due to combat and/or terror attacks is associated with high mortality. The successful management includes the use of "rescue" extracorporeal lung assist and early transport by aeromedical evacuation teams. AIMS Description of the pre-hospital support of a severely injured soldier with a pumpless extracorporeal arterio-venous lung assist in critica...

endotracheal tube (ett) cuff herniation is a rare, and often difficult to diagnose, cause of bronchial obstruction. we present a case of outside cuff herniation of an endotracheal tube that caused pulmonary right lung atelectasis. a 29-year-old man ,a case of car accident with multiple fractures, was admitted to the emergency ward and transferred to the operating room(or) for open reduction and...

BACKGROUND We aimed to investigate the relationship between increased free fatty acid (FFA) level and early postoperative hypoxemia after coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB). METHODS Ninety-eight consecutive patients undergoing CABG were enrolled. Early postoperative hypoxemia was defined as the lowest of the ratio of arterial oxygen tension (PaO2) to insp...

Committee News| June 2023 Deliberate Oxygen Therapy – How Much Is Too of a Good Thing? Jeffrey M. Carness, MD, FASA; FASA Search for other works by this author on: This Site PubMed Google Scholar Catherine Kuza, FASA, FCCM ASA Monitor 2023, Vol. 87, 33. https://doi.org/10.1097/01.ASM.0000938860.68159.a4 Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Shar...

Cigarette smoking (CS) aggravates post-traumatic acute lung injury and increases ventilator-induced lung injury due to more severe tissue inflammation and apoptosis. Hyper-inflammation after chest trauma is due to the physical damage, the drop in alveolar PO2, and the consecutive hypoxemia and tissue hypoxia. Therefore, we tested the hypotheses that 1) CS exposure prior to blunt chest trauma ca...

BACKGROUND AND OBJECTIVES Nocturnal hypoxemia is highly prevalent among patients with CKD. Nocturnal hypoxemia contributes to systemic inflammation, oxidative stress, endothelial cell dysfunction, and activation of the renin-angiotensin system, which are common pathologic mechanisms of CKD progression. This study investigated whether nocturnal hypoxemia is independently associated with CKD prog...

BACKGROUND The purpose of this study is to identify the risk factors for postoperative hypoxemia in patients with Stanford A aortic dissection surgery and their relation to clinical outcomes. METHODS Clinical records of 186 patients with postoperative hypoxemia in Stanford A aortic dissection were analyzed retrospectively. The patients were divided into two groups by postoperative oxygen frac...