conclusions intake of water extract of silybum marianum is a useful treatment for liver function in drug-induced fatty liver. results concentrations of hdl-c and protein decreased and activity of alt increased in tmx group compared with the control group. the sme increased protein concentration and decreased alt activity in tmx-sme group compared with the tmx group. histopathological examinatio...

Background: Obesity is one of the cardiovascular disease risk factors that cause hypertrophy or hyperplasia adipocytes. Changes in fat cells have potential to increase inflammation and insulin resistance. Objective: This study aims determine effects high glucose, egg yolk consumption, calorie restriction, air pollution on body weight, cell size, tissue weight rats. Methods: The type experimenta...

objective: this study aims to evaluate the protective effects of american ginseng administered by gastric intubation on sperm vital quality in adult male rats treated with cyclophosphamide (cp). materials and methods: in this experimental study, 28 adult male wistar rats were assigned to four groups, seven rats in each. the animals allocated to control, cp treated, ginseng treated and cp-ginsen...

The aim of the present study was to investigate toxic effects aluminum chloride (AlCl3) on reproductive organs, as well as, protective effect propolis against AlCl3-induced toxicity in male rats. Eighty adult fertile Sprague Dawley albino rats were randomly divided into four groups 20 each. Group 1: served control group and received only distilled water. 2: a daily ingestion 80 mg/kg AlCl3. 3: ...

results the present study revealed that the sobt and sop extracts showed in vitro bactericidal activity against gram-positive and gram-negative bacteria. furthermore, administration of sobt and sop increased the rats’ survival rates by 66.7% and 83.33%, respectively, as compared to the untreated clp-septic rats. treatment of the clp-septic rats with sobt and sop significantly alleviated alterat...

Objective: This study was to evaluate the effect of Vitamin C on the histology and histochemistry of the prefrontal cortex of ethanol-induced rats. Methods: Male Sprague-Dawley rats were used for the study. Ethical approval was obtained from the University’s ethical committee. The rats were randomly divided into 6 groups of 10 rats each. Rats in group A= free access to normal saline. Rats in gr...

Objective: This study was to evaluate the effect of Vitamin C on the histology and histochemistry of the prefrontal cortex of ethanol-induced rats. Methods: Male Sprague-Dawley rats were used for the study. Ethical approval was obtained from the University’s ethical committee. The rats were randomly divided into 6 groups of 10 rats each. Rats in group A= free access to normal saline. Rats in gr...

objective: this study was designed to investigate the antinociceptive effect of chronic administration of the flavonoid hesperetin in streptozotocin-diabetic rats using formalin and hot tail immersion tests. materials and methods: rats were divided into 5 control groups, hesperetin-treated control, diabetic, sodium salicylate (ss)-treated diabetic, and hesperetin- and glibenclamide-treated dia...

objective(s): auraptene, a monoterpene coumarin from citrus species, exhibits cardioprotective effects.in this study, the effects of auraptene administration were investigated on blood pressure of normotensive and desoxycorticosterone acetate (doca) salt induced hypertensive rats. materials and methods: five weeks administration of auraptene (2, 4, 8 and 16 mg/kg/day) and nifedipine (0.25, 0.5,...

objective(s) gastric ulceration is induced by various forms of stress like surgery, ischemia and trauma. the female sex has more resistance to stress and the gastrointestinal lesions happen fewer than male sex. the purpose of this study was to evaluate the role of estradiol and progesterone on the gastric acid and pepsin levels following traumatic brain injury (tbi) induction. materials and met...