نتایج جستجو برای: treatment initiation timing

تعداد نتایج: 1545714  

2016
Khaled Rahmani Shahin Yarahmadi Koorosh Etemad Ahmad Koosha Yadollah Mehrabi Nasrin Aghang Hamid Soori

CONTEXT Appropriate management of neonates, tested positive for congenital hypothyroidism (CH), in particular, the initial dosage of levothyroxine and the time of initiation of treatment is a critical issue. The aim of this study was to assess all current evidence available on the subject to ascertain the optimal initial dose and optimal initiation time of treatment for children with CH. EVID...

Journal: :PLoS Medicine 2008
Steven B Welch Di Gibb

BACKGROUND TO THE DEBATE The advent of highly active antiretroviral therapy (HAART) dramatically improved the prognosis for both adults and children infected with HIV who had access to treatment. However, the optimal timing for initiating treatment remains controversial, particularly in children. This debate lays out the case for deferred treatment against the case for early initiation of HAART...

2015
Lieketseng J Masenyetse Samuel OM Manda Henry G Mwambi

BACKGROUND Antiretroviral treatment (ART) has been effective in reducing HIV/AIDS related morbidity and mortality. However, the use and uptake of ART has resulted in adverse reactions, due mainly to the medicine's toxicity and interactions with other medicines. The timing of adverse drug reactions (ADRs) among these patients is a critical public health issue for antiretroviral (ARV) treatment a...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012
Diana M Negoescu Douglas K Owens Margaret L Brandeau Eran Bendavid

We developed a mathematical model to identify the timing of antiretroviral therapy (ART) initiation that optimizes patient outcomes as a function of patient CD4 count, age, cardiac mortality risk, sex, and personal preferences. Our goal was to find the conditions that maximize patient quality-adjusted life expectancy (QALE) in the context of our model. Under the assumption that ART confers dise...

2011
Kenneth Yong Gursharan Dogra Neil Boudville Mary Pinder Wai Lim

This paper addresses the epidemiology of AKI specifically in relation to recent changes in AKI classification and revisits the controversies regarding the timing of initiation of dialysis and the use of peritoneal dialysis as a renal replacement therapy for AKI. In summary, the new RIFLE/AKIN classifications of AKI have facilitated more uniform diagnosis of AKI and clinically significant risk s...

Journal: :Journal of virology 2014
Maria J Buzon Enrique Martin-Gayo Florencia Pereyra Zhengyu Ouyang Hong Sun Jonathan Z Li Michael Piovoso Amy Shaw Judith Dalmau Nadine Zangger Javier Martinez-Picado Ryan Zurakowski Xu G Yu Amalio Telenti Bruce D Walker Eric S Rosenberg Mathias Lichterfeld

UNLABELLED Initiation of antiretroviral therapy during the earliest stages of HIV-1 infection may limit the seeding of a long-lasting viral reservoir, but long-term effects of early antiretroviral treatment initiation remain unknown. Here, we analyzed immunological and virological characteristics of nine patients who started antiretroviral therapy at primary HIV-1 infection and remained on supp...

2011
Jeonghui Lee Se Kyung Lee Sangmin Kim Min Young Koo Min-Young Choi Soo Youn Bae Dong Hui Cho Jiyoung Kim Seung Pil Jung Jun-Ho Choe Jung-Han Kim Jee Soo Kim Jeong Eon Lee Jung-Hyun Yang Seok Jin Nam

PURPOSE The frequency of immediate breast reconstruction (IBR) is increasing, and the types of reconstruction used are diverse. Adjuvant chemotherapy is a life-saving intervention in selected high-risk breast cancer patients. The aim of our study was to determine how IBR and type of reconstruction affect the timing of the initiation of chemotherapy. METHODS We obtained data from female breast...

Journal: :Ear, nose, & throat journal 2005
Aydin Mamak Süleyman Yilmaz Harun Cansiz Ender Inci Ender Güçlü Levent Dereköylü

We investigated the prognostic significance of the presence or absence of vertigo and tinnitus, the timing of the initiation of treatment, the type and severity of hearing loss, and age in 72 patients who had experienced sudden hearing loss. We found that the factors associated with a positive prognosis were the absence of vertigo, the presence of tinnitus, initiation of treatment within 7 days...

Journal: :Clinical Journal of the American Society of Nephrology 2010

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