Introduction: Radioimmunotherapy (RIT) is a very promising new therapy for the treatment of recurrent B-Cell non-Hodgkin's lymphoma (NHL). Iodine-131 is the most frequently used nuclide in clinical RIT, but its usefulness has been limited by dehalogenation of monoclonal antibodies labeled via conventional methods. To circumvent this problem, we have synthesized a tr...

BACKGROUND Trichloroacetic acid, an oxidative metabolite of trichloroethylene (TRI), is a ligand of the peroxisome proliferator-activated receptor alpha (PPAR) alpha, which is involved in lipid homeostasis and anti-inflammation. OBJECTIVE We examined the role of mouse and human PPARalpha in TRI-induced hepatic steatosis and toxicity. METHODS Male wild-type (mPPARalpha), Pparalpha-null, and ...

The Two-Way Task: Run1: TAC-M, TS-M, and Tri-BM Run2: TAC-M, TS-M, and BoW-BM Run3: TAC-M, TS-M, NE-M, & Tri-BM, BoW-BM The Three-Way Task: Run1: TAC-M, TS-M, and Tri-BM, BoWBM Run2: TAC-M, TS-M, NE-M (partial), and Tri-BM, BoW-BM Run3: TAC-M, TS-M, NE-M, and Tri-BM, BoW-BM From Two-Way to Three-Way: If BoW-BM=YES & Tri-BM=NO then CONTRADICTION If BoW-BM=YES & Tri-BM=YES then ENTAILMENT Others ...

This study was undertaken to clarify the effect of enzymes induced by ethanol consumption on the pharmacokinetics of trichloroethylene (TRI, a highly metabolised substance) and 1,1,1-trichloroethane (1,1,1-TRI, a poorly metabolised substance). Rats maintained on a control liquid diet or a liquid diet containing ethanol (2 g/day/rat) for not less than three weeks were exposed to either TRI (50, ...

Les index bitmaps sont souvent utilisés pour indexer des données multidimensionnelles. Ils utilisent principalement l’accès séquentiel aux données, tant à l’écriture qu’à la lecture. Les bitmaps peuvent être compressés pour réduire le coût des entrées/sorties tout en minimisant l’utilisation du microprocesseur. Les techniques de compression les plus efficaces sont fondées sur la compression par...

AIMS Transradial coronary intervention (TRI) introduces a trauma to the radial artery (RA), possibly influencing quality as a bypass conduit if subsequently used. We sought to determine the acute and chronic effects of TRI on the RA by optical coherence tomography (OCT). METHODS AND RESULTS Immediately after TRI completion, 73 RAs in 69 patients were examined. The sheath was pulled back 2 cm ...

The advantages of triple-site ventricular pacing (Tri-V) compared to conventional biventricular site pacing (Bi-V) have been reported. We sought to identify the predictors of acute hemodynamic Tri-V responders. Acute hemodynamic studies were performed in 32 patients with advanced heart failure during Tri-V implantation. After the right ventricular (RV) and left ventricular (LV) leads were impla...

A growing body of evidence now supports the use of transradial percutaneous intervention (TRI) as the preferred access site for the treatment of patients with ST-segment elevation myocardial infarction (STEMI). Historically, TRI has been avoided in the STEMI population due to concerns over longer procedure time, longer door-to-device time, higher crossover rates, and the experience level requir...